Lei Chen MD MHS

Associate Professor of Pediatrics (Emergency Medicine); Director of Research, Pediatric Emergency Medicine

Research Interests

Emergency ultrasound; Ethics and subject protection; Student, resident and fellow education; Serious bacterial infections in infants; Pediatric resuscitations, Global Health

Current Projects

Recognition of pediatric sepsis in Rwandan hospitals.

Epdemiology of admissions to a newly-opened pediatric intensive care unit in Rwanda.

Developing a low-cost high flow nasal cannula system for resource-limited settings.

Developing a clinical research curriculum for facutly and traineeds, Changsha, China.

Use of bedside ultrasound in resource-limited settings.


Research Summary

I am committed to a career in Health Services Research as a means to improve the care of children in the acute care setting. My short-term goal is to gain additional knowledge in health care management and policy and in assessing cost-effectiveness as well as efficiency of clinical interventions based on emerging technologies. My long-term career goal is to develop the expertise to design, to implement, and to evaluate the clinical and public health effectiveness of interventions that employ new emerging technologies for the acute care of children.

I have focused on the application of new technology to improve the care of pediatric patients in the emergency department. Broadly speaking these projects have one or both of the following goals:

  • increase efficiency of medical care;
  • enhancing the safety of the patients during the delivery of medical care.
  • improved delivery of quality health care in developing world settings.

Extensive Research Description

I am committed to a career in Health Services Research as a means to improve the care of children in the acute care setting. My short-term goal is to gain additional knowledge in health care management and policy and in assessing clinical and cost-effectiveness as well as efficiency of clinical interventions based on emerging technologies. My long-term career goal is to develop the expertise to design, to implement, and to evaluate the clinical and public health effectiveness of interventions that employ new emerging technologies for the acute care of children.

During the past several years I have focused on the application of new technology to improve the care of pediatric patients in the emergency department. Broadly speaking these projects have one or both of the following goals; 1) increase efficiency of medical care; and 2) enhancing the safety of the patients during the delivery of the medical care.

Most recently my efforts have focused on improving the health care of children in developing countries. To that end my projects have focused on

1. Improving the infrastructure and training for clinical research

2. Improving the medical education.

The two countries where I have devoted most of my time are Rwanda and China.


Selected Publications

  • Riera A, Hsiao AL, Langhan ML, Goodman TR, Chen L. Diagnosis of Intussusception by Physician Novice Sonographers in the Emergency Department. Annals of Emergency Medicine. 2012;60(3):264-268
  • Riera A, Chen L. Ultrasound evaluation of skull fractures in children: a feasibility study. Pediatric Emergency Care. 2012;28(5):420-5
  • Faustino E, Spinella P, Li S, Pinto MG, Stoltz P, Tala J, Card M, Northrup V, Baker K, Goodman T, Chen L, Silva C. Incidence and Acute Complications of Asymptomatic Central Venous Catheter–Related Deep Venous Thrombosis in Critically Ill Children. The Journal of Pediatrics. 162(2): 387-391.
  • Vieira RL, Hsu D, Nagler J, Chen L, Gallagher R, Levy JA. Pediatric emergency medicine fellow training in ultrasound: consensus educational guidelines. Academic Emergency Medicine. 2013 Mar;20(3):300-6
  • Chen L, Hsiao A, Langhan M, Riera A, Santucci K. Use of bedside ultrasound to assess degree of dehydration in children with gastroenteritis, Academic Emergency Medicine, 2010; 17(10): 1042–1047
  • Hsiao, A, Chen, L, Baker, M (2006) Incidence and predictors of serious bacterial infections among 57 to180-day-old infants, Pediatrics, 117(5)1695-1701, Published
  • Chen, L, Hsiao, A, Moore, C, Dziura, J, Santucci, K (2005) Utility of bedside bladder ultrasound prior to urethral catheterization in young children, Pediatrics, 115(1)108-111, Published
  • Chen L, Hsiao A, Randomized trial of endotracheal tube versus laryngeal mask airway in simulated pre-hospital pediatric arrest. Pediatrics. 2008; 122(2): e294-e297
  • Langhan M, Chen L, Current Utilization of Continuous End-Tidal Carbon Dioxide Monitoring in Pediatric Emergency Departments. Pediatric Emergency Care. 2008; 24(4):211-213
  • Chen L, Kim Y, Santucci KA. Use of ultrasound measurement of the inferior vena cava diameter as an objective tool in the assessment of children with clinical dehydration. Academic Emergency Medicine, 2007; 14(10):841-845

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