Intranet | Faculty By Department | Immunobiology Listings

Immunobiology Faculty

Richard Flavell

Chair

Sterling Professor of Immunobiology
Investigator, Howard Hughes Medical Institute
Department Chair, Immunobiology

Research Interests:Animal Models; Autoimmunity; Diabetes; Gene Expression; Gene Transfer; Genes; Immune System; Lyme Borreliosis Or Lyme Disease; Molecular Cellular Entities; Recombinant DNA; Transgenic Animals; Autoimmunity; Knockout Mice; Lyme Disease; T Cell Lineages; Tolerance; Transgenic Mice

Jeffrey Bender

Robert I. Levy Professor of Medicine (Cardiology) and Professor of Immunobiology
Associate Chief, Cardiovascular Medicine

Research Interests:Inflammatory, Immune, Metabolic and Hormonal Effects on the Endothelium

Clinical Interests:Clinical cardiology; preventive cardiology

Alfred Bothwell

Professor of Immunobiology
Director of Graduate Studies

Research Interests:Human T cell recognition; inflammation and cancer; type 1 diabetes; function of PPARs

Clinical Interests:Studies of human T cell recognition of human endothelial cells. The research goals of the Bothwell lab are to characterize the development and function of T cells and to characterize mechanisms that affect T cell recognition and recruitment into vascular sites. In addition, humanized mouse models are being established to study type 1 diabetes and breast cancer.

Lieping Chen

United Technologies Corporation Professor in Cancer Research and Professor of Immunobiology, of Dermatology and of Medicine (Medical Oncology)
Director, Cancer Immunology Program at Yale Cancer Center

Research Interests:Co-signaling molecules, costimulation, coinhibition, modulation of immune responses, molecular mechanisms of lymphocyte activation and deactivation

Tian Chi

Associate Professor of Immunobiology

Research Interests:Epigenetic memory; transgenerational inheritance; chromatin biology

Joseph Craft

Paul B. Beeson Professor of Medicine (Rheumatology) and Professor of Immunobiology
Section Chief, Rheumatology
Program Director, Investigative Medicine
Paul B. Beeson Professor of Medicine

Research Interests:Arthritis; Autoimmunity; Cytokines; Diseases and Disorders; Lupus; T Cell Differentiation; T Cells; Tolerance

Clinical Interests:Systemic lupus; Autoimmune diseases; Internal medicine; arthritis

Peter Cresswell

Eugene Higgins Professor of Immunobiology and Professor of Cell Biology and of Dermatology

Research Interests:Molecular mechanisms of antigen processing; assembly and intracellular transport of CD1 molecules, class I and class II MHC molecules; effector functions and mechanisms of action of interferon-induced proteins; viral immunity

Madhav Dhodapkar

Arthur H. and Isabel Bunker Professor of Medicine (Hematology) and Professor of Immunobiology
Chief, Section of Hematology, Department of Internal Medicine
Clinical Research Program Leader, Hematology Program, Yale Cancer Center

Research Interests:Myeloma and related plasma cell disorders; human immune system's interaction with growing tumors in patients; preneoplastic monoclonal gammopathy and multiple myeloma, tumor and host related factors

Clinical Interests:Multiple myeloma; monoclonal gammopathy of unknown significance (MGUS); immunobiology of cancers

Stephanie Eisenbarth

Assistant Professor of Laboratory Medicine, of Immunobiology and of Medicine (Immunology)
Assistant Director, Clinical Immunology & Flow Cytometry Laboratories
Director, Immune Monitoring Core

Research Interests:Pattern Recognition Receptors; NOD-like Receptors (NLRs); Dendritic Cells; T cells; Allergy/Asthma; Vaccines/Adjuvants; Red Blood Cell Alloimmunization; Autoimmune Diabetes; Influenza

Clinical Interests:The Clinical Immunology Laboratory integrates standard diagnostic immunology testing with an active flow cytometry and molecular diagnostics laboratory and therefore services a large and diverse patient population. The Immune Monitoring Core provides a core resource for clinical and translational research protocols at Yale School of Medicine that involve immunotherapy and/or that affect the human immune system. In addition to performing assays beyond the scope of routine clinical tests, this facility is involved in developing and utilizing new technologies and assays as needed for basic and clinical human studies on-going at Yale.

Jack Elias

Waldemar Von Zedtwitz Professor of Medicine and Professor of Immunobiology
Chair, Department of Internal Medicine

Research Interests:Cell and Molecular biology of lung injury and repair; Asthma; COPD; Pulmonary fibrosis; acute lung injury; Cytokines; Inflammation; Internal Medicine; Pulmonary Diseases; Transgenic mice; genetically modified mice; Emphysema; Fibrosis; Inflammation

Clinical Interests:Asthma; Chronic Obstructive Pulmonary Disease (COPD); emphysema; pulmonary vasculitis; interstitial lung diseases; pulmonary fibrosis; cancer; acute lung injury

Daniel Goldstein

Associate Professor of Medicine (Cardiology) and of Immunobiology

Research Interests:immunity in transplantation; impact of aging on inflammation and immunity

Clinical Interests:Clinical cardiology; heart failure/cardiac transplantation

David Hafler

Gilbert H. Glaser Professor of Neurology and Professor of Immunobiology
Chair, Department of Neurology

Research Interests:Neuroimmunology; Multiple Sclerosis; Autoimmunity; Genetics; Immunobiology

Clinical Interests:Neuroimmunology and Multiple Sclerosis

Kevan Herold

Professor of Immunobiology and of Medicine (Endocrinology)
Deputy Director for Translational Science, YCCI

Research Interests:Type 1 diabetes; immune therapy; autoimmunity

Clinical Interests:Diabetes mellitus; hypoglycemia; endocrinology

Akiko Iwasaki

Professor of Immunobiology and of Molecular, Cellular, and Developmental Biology
Professor of Molecular Cellular and Developmental Biology
Howard Hughes Medical Investigator

Research Interests:Innate immunity; Autophagy; Inflammasomes; sexually transmitted infections; Herpes simplex virus; human papillomavirus;respiratory virus infections; Influenza infection; T cell immunity; Commensal bacteria

Susan Kaech

Associate Professor of Immunobiology
HHMI Early Career Scientist

Research Interests:Mechanisms of memory T cell development; Developmental Biology; Immunobiology; Immunology; Vaccine; Immunobiology; T-Cells; Vaccines; Adaptive immunity and immunological memory to viruses

Paula Kavathas

Professor of Laboratory Medicine, of Genetics, of Immunobiology and of Molecular, Cellular, and Developmental Biology
Associate Chair for Research
Director, Science Education Outreach Program

Research Interests:Gene Regulation; Immunology; Molecular Cellular Entities; Receptors; Structure or Function (Health or Safety or Medical); Transgenic Animals

Martin Kriegel

Assistant Professor of Immunobiology and of Medicine (Rheumatology)
Assistant Professor of Medicine (Rheumatology)

Research Interests:Microbiome; commensals; lymphocytes; autoimmunity; Th17 cells; antiphospholipid syndrome; beta2-glycoprotein; lupus; type 1 diabetes

Clinical Interests:Systemic autoimmune diseases; antiphospholipid syndrome; systemic lupus erythematosus; vasculitis; myositis

Ruslan Medzhitov

David W. Wallace Professor of Immunobiology
Investigator, Howard Hughes Medical Institute

Research Interests:Inflammation; Allergy; Immunology; Innate Immunity; Pathophysiology

Eric Meffre

Associate Professor of Immunobiology and of Medicine (Immunology)

Research Interests:Human B-cell tolerance; Primary immunodeficiencies; Autoimmune diseases

João Pereira

Assistant Professor of Immunobiology

Research Interests:Immunology; Hematopoiesis; B-lymphocyte development; Bone marrow niches; Cell migration

Jordan Pober

Bayer Professor of Immunobiology and Professor of Dermatology and of Pathology
Director, Human and Translational Immunology Program
Vice-Chair, Dept. of Immunobiology for the Section of Human and Translational Immunology

Research Interests:Immunobiology of vascular endothelial cells: cytokine actions and mechanisms; transplantation immunology

Carla Rothlin

Assistant Professor of Immunobiology

Research Interests:Regulation of inflammation; homeostatic control of the immune system

David Schatz

Professor of Immunobiology
Professor of Molecular Biophysics and Biochemistry

Research Interests:Biochemical mechanism and developmental regulation of V(D)J recombination and somatic hypermutation; lymphocyte development; mechanisms of DNA repair; function of the RAG1 and RAG2 proteins; mechanisms of lymphomagenesis

Mark Shlomchik

Professor of Laboratory Medicine and of Immunobiology
Associate Director, Transfusion Service

Research Interests:Autoimmunity; Blood or Blood Products or Transfusions; Bone Marrow Transplantation; Immunobiology; Immunology; Immunopathology; Immunotherapy; Lymphocytes; Transgenic Animals

Clinical Interests:Transfusion medicine; stem cell collection and processing; apheresis

Warren Shlomchik

Associate Professor of Medicine (Hematology), of Immunobiology and of Medicine (Hematology)

Research Interests:Mechanisms of antigen presentation; T cell effector function and regulation of Graft-vs.-Host Disease and Graft-vs.-Leukemia

Clinical Interests:Bone marrow transplant

Bing Su