Emily J. Gilmore MD
Assistant Professor of Neurology; Staff Neurointensivist, Neuroscience Intensive Care Unit
Neurocritical care; Neuromonitoring; Multimodality monitoring; Acute stroke; Hypothermia
I am a sub-investigator for the following clinical trials:
GAMES - study of IV glyburide for cerebral edema following acute ischemic stroke
HI-DEF - study of deferoxamine mesylate for intracerebral hemorrhage
ATACH II - study of aggressive blood pressure lowering for intracerebral hemorrhage
CLEAR III - study of intraventricular tPA for intraventricular hemorrhage
DIAS 4 - study of desmoteplase for thrombolysis of acute ischemic stroke
ICTuS 2/3 - study of induced hypothermia in acute ischemic stroke
My research to date has focused on the use of continuous EEG (cEEG) monitoring in patients with severe brain injury, either secondary to a primary brain process or as a manifestions of systemic disease.
My most recent project was a prospective study in Medical ICU patients with severe sepsis who were connected to EEG monitoring. Patients with severe sepsis are at an increased risk of developing frank seizures and abnormal brain wave patterns that represent an increased risk for developing seizures. Our goal was to assess the incidence of seizures and abnormal brain wave patterns as well as the effect of such findings on short and long-term outcomes in this population.
I have also authored chapters on neuromonitoring and have experience with multimodalty monitoring, which involves using information from probes placed in the acutely injured brain of comatose patients to guide medical management.
Currently, I am a site co-investigator for several national clinical trials that are enrolling patients admitted to the Neuroscience ICU with acute ischemic stroke. In addition, I am involved in a study with the Epilepsy Division using a newer antiepileptic (lacosamide) in the treatment of electrographic seizures.