Emanuela Marina Bruscia, PhD

Assistant Professor of Pediatrics (Respiratory)

Research Organizations

Pediatrics: Pediatric Respiratory Medicine

Research Summary

Our research aims to understand how CFTR--the gene that, when mutated, causes Cystic Fibrosis (CF)--affects innate immunity and how this will impact the progression of CF lung disease. We have performed pioneering studies demonstrating that CFTR expression is necessary for the normal function of an important player of the innate immune response: macrophages. Using in vitro and in vivo models, we are dissecting the molecular mechanisms by which CFTR affects these cells.

Extensive Research Description

Selected Publications

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Contact Info

Emanuela Marina Bruscia, PhD
Mailing Address
Yale PediatricsPO Box 208064
New Haven, CT 06520-8064