Douglas E Brash PhD

Senior Research Scientist in Therapeutic Radiology and in Dermatology and Clinical Professor of Therapeutic Radiology

Departments & Organizations

Radiobiology & Radiotherapy

Dermatology: Skin Diseases Research Center, Yale

Therapeutic Radiology/Radiation Oncology: Radiobiology

Radiobiology and Radiotherapy

Research Interests

Ultraviolet Light; Skin Cancer more...


  • B.S., University of Illinois, 1973
  • Ph.D., Ohio State University, 1979

Selected Publications

  • Rochette, PJ and Brash, DE. Human telomeres are hypersensitive to UV-induced DNA damage and refractory to repair. PLoS Genetics 6 (e1000926): 1-13, 2010.
  • Klein, AM, Brash, DE, Jones, PH, and Simons, BD. Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UVB during preneoplasia. Proc. Natl. Acad. Sci. USA. 107:270-275, 2010.
  • Knezevic, D, et al. Bcl-2 is the target of a UV-inducible apoptosis switch and a node for UV signaling. Proc. Natl. Acad. Sci. USA. 104:11286-91, 2007.



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