Dianqing (Dan) Wu PhD

Professor of Pharmacology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology

Stem Cell Center, Yale: Stem Cell Niche and Homing | Signal Transduction and Cell Growth

Signal Transduction

Vascular Biology and Therapeutics Program


Research Interests

Wnt; signal transduction; G protein, Chemotaxis;Cell migration; Cancer biology and therapeutics; Stem cell biology; Chemoattractant signaling; Inflammation  more...


  • BS, Nanjing University, 1985
  • Ph.D., Clarkson University, 1991

Selected Publications

  • Gan, X., Wang, J., Wang, C., Sommer, E., Kozasa, T., Srinivasula, S., Alessi, D., Offermanns, S., Simon, M.I., and Wu, D. (2012). PRR5L degradation promotes mTORC2-mediated PKC-d phosphorylation and cell migration downstream of Ga12. Nat Cell Biol. 10.1038/ncb2507
  • Tang, W., Zhang, Y., Xu, W., Harden, T.K., Sondek, J., Sun, L., Li, L., and Wu, D. (2011). A PLCb/PI3Kg-GSK3 Signaling Pathway Regulates Cofilin Phosphatase Slingshot2 and Neutrophil Polarization and Chemotaxis. Developmental Cell 21, 1038-1050.
  • Xu, W., Wang, P., Petri, B., Zhang, Y., Tang, W., Sun, L., Kress, H., Mann, T., Shi, Y., Kubes, P., and Wu, D. (2010). Integrin-induced PIP5K1C kinase polarization regulates neutrophil polarization, directionality, and in vivo infiltration. Immunity 33, 340-350.



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