Daniel Alfonso Colon-Ramos, PhD

Associate Professor of Cell Biology

Departments & Organizations

Cell Biology: Colon-Ramos lab | Developmental Cell Biology and Genetics

Interdepartmental Neuroscience Program


Office of Student Research

Program in Cellular Neuroscience, Neurodegeneration and Repair

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development: Cytoskeleton and Cell Morphogenesis; Developmental Biology; Genetics and Genomics | Neuroscience: Axon Guidance; Development; Molecular/Cellular Neuroscience; Neuroimaging


Daniel Colón-Ramos was born and raised in Puerto Rico. He completed his B.A. at Harvard University, where he did research, in collaboration with the Smithsonian Tropical Research Institute, on the use of medicinal plants by indigenous groups in Central America. He then completed his PhD in the lab of Dr. Sally Kornbluth at Duke University, where he combined bioinformatics, molecular biology, biochemistry and cell biological approaches to answer questions critical for understanding the molecular mechanisms of apoptosis, a physiological process tightly linked to cancer. He then trained in molecular genetics, physiology and neurobiology as a postdoctoral fellow in the lab of Dr. Kang Shen at Stanford University.

The Colón-Ramos lab is interested in understanding the developmental events that direct precise neural connectivity. In particular, we are interested in how these events are coordinated in complex neuropil structures such as the brain. How are these developmental events simultaneously coordinated between pre- and postsynaptic partners to allow precise wiring? How do they give rise to highly organized neuropil structures such as the brain? We use the nematode C. elegans to look at the development of circuits in vivo and with single cell resolution.

We study how neural circuits form, how they influence behavior, and how they are changed during learning

Education & Training

PhD Duke University Medical Center (2003)
AB Harvard College (1998)
Postdoctoral fellow Stanford University

Honors & Recognition

  • AAAS Early Career Award for Public Engagement with ScienceAmerican Association for the Advancement of Science (2012)

  • Sloan Research Fellow (2010)

  • Klingenstein Fellowship Award in the Neurosciences (2009)

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Contact Info

Daniel Alfonso Colon-Ramos, PhD
Office Location
Boyer Center for Molecular Medicine
295 Congress Avenue, Ste Room 436B

New Haven, CT 06510
Mailing Address
PO Box 208002
333 Cedar Street

New Haven, CT 06520-8002

Colon-Ramos Lab