Cynthia A Brandt MD, MPH

Professor of Emergency Medicine and of Anesthesiology (Medical Informatics)

Research Interests

Biomedical informatics; Health services; Veterans

Current Projects

VA Special Informatics Fellowship: this project trains future scientists in informatics at the VA.
Women Veterans Cohort Study: this project is study Veterans returning from Iraq and Afghanistan, and looking at differences between males and females for healthcare costs, utilization and co-morbidities.
Consortium for Healthcare Informatics Research: this is a VA funded multi-site collaboration studying methods to use the text in the VA's electronic medical record.

Research Summary

Much of my work has focused on building informatics infrastructure for clinical research, working closely with many clinical research groups, and performing research focused on issues such as the management of clinical vocabularies used in clinical research databases and implementation of computerized clinical practice guidelines. Another focus is primarily informatics research working on the development and the application and use of open-source informatics tools for information retrieval and information extraction from the VA’s electronic medical record free-text data.

Extensive Research Description

I have worked for years building informatics infrastructure for clinical research, working closely with many clinical research groups, and performing research focused on issues such as the management of clinical vocabularies used in clinical research databases and implementation of computerized clinical practice guidelines. I am a co-copyright holder and have been extensively involved with the development of TrialDB an open-source, web-based clinical research data management system that is used by multiple healthcare institutions and universities in the US and internationally. Additionally I currently provide mentoring and training for both Yale national library of medicine informatics fellows and pre-doctoral students, and VA special informatics fellows. Research projects with fellows have included broad informatics domains including: clinical guidelines, clinical research databases, natural language processing, the design and application of informatics tools, personal health records, handheld computing, evaluation of informatics projects, and the design and use of electronic medical record data for quality, health services research and clinical decision support. Informatics is an interdisciplinary specialty and my past mentees have included emergency medicine, primary care and other types of clinicians, nurses and computer scientists. I also have extensive experience in health services research and currently have funded projects that use VA EMR (VistA) and administrative (NPCD, DSS) and CDW data.


Selected Publications

  • Garla V, Lo Re V, Dorey-Stein Z, Kidwai F, Scotch M, Womack J, Justice A, Brandt C. The Yale cTAKES Extensions for Document Classification: Architecture and Application, J Am Med Inform Assoc.
  • Benin A, Fenick A,Herrin J, Vitkauskis G, Chen J, Brandt C. Validation of metrics of quality based on data from an electronic health record. American Journal of Medical Quality.
  • Konovalov S, Scotch M, Post L, Brandt CA, Biomedical Informatics Techniques for Processing and Analyzing Web Blogs of Military Service Members, J Med Internet Res, Vol 12, No 4 (2010), Oct-Dec, http://www.jmir.org/2010/4.
  • Womack J, Scotch M, Gibert C, Chapman W, Yin M, Justice AC, Brandt CA. A Comparison of Two Approaches to Text Processing: Facilitating Chart Reviews of Radiology Reports in electronic Medical Records. Perspective in Health Information Management, Fall 2010, http://perspectives.ahima.org/.
  • Haskell SG, Krebs E, Goulet J, Mattocks K, Skanderson M, Justice A, Brandt CA. The burden of illness in the first year home: do male and female VA users differ in health conditions and healthcare utilization. Women’s Health Issues. 2010 Oct 5;12(4):e45.

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