Comparative Medicine Faculty

Tamas Horvath

Chairman

Jean and David W. Wallace Professor of Comparative Medicine and Professor of Neurobiology and of Obstetrics, Gynecology, and Reproductive Sciences
Chair, Section of Comparative Medicine
Jean and David W. Wallace Professor of Biomedical Research, Director, Yale Program in Integrative Cell Signaling and Neurobiology of Metabolism

Research Interests:Neurobiology of obesity; Neuroendocrine physiology

Clinical Interests:Neurodegenerative diseases; aging; diet; nutrition

Carmen Booth

Assistant Professor of Comparative Medicine
Co-director, Mouse Phenotyping Service

Research Interests:Pathology of genetically engineered mice; Pathology of inflammation; Pathology of aging; Veterinary Pathology; Mouse pathology; phenotyping; Hemophilia in rats

Janet Brandsma

Associate Professor (Adjunct) of Comparative Medicine and of Pathology

Research Interests:Molecular biology of papillomavirus pathogenesis; Development of protective and therapeutic vaccines for the treatment of human papillomavirus (HPV)-associated disease; Vaccines; Virology

Susan Compton

Research Scientist in Comparative Medicine
Director, Molecular, Serological and Virological Diagnostics

Research Interests:Pathogenesis of rodent viral infections; Diagnostic Virology; Bacterial Expression Systems; Communicable Diseases; Disease Control; Disease Model; Eukaryotic Expression Systems; Gastrointestinal Infection; Host Organism Interaction; Immunization; Immunoassay; Infectious Diseases/Agents; Intestinal Mucosa; Laboratory Mouse; Laboratory Rat; Molecular Probes; Murine Hepatitis Virus; Norovirus; Parvovirus; Pathogenesis; Polymerase Chain Reaction; Rat Coronavirus; Receptor Binding; Respiratory Diseases; RT-RCR; Serology; Sialodacryoadenitis Virus; Site Directed Mutagenesis; Vaccine; Viral Studies; Virion; Virology; Virulence; Virus Infection Mechanism; Virus Protein; Virus Receptor; Western Blotting

James Goodrich

Assistant Professor of Comparative Medicine

Research Interests:Animal Models of Menopause and Cardiovascular Disease

Mihaly Hajos

Professor (Adjunct) of Comparative Medicine

Research Interests:systems neurophysiology; biomarkers; schizophrenia; Alzheimer's disease, Huntington's disease, neuropharmacology

Robert Jacoby

Professor Emeritus of Comparative Medicine
Chief, Clinical Services, Yale Animal Resources Center

Research Interests:Pathogenesis of rodent viral infections; Laboratory Animal Pathology; Vivarium Management; Laboratory Animal Medicine; Pathology

Matthew Lawrence

Assistant Professor (Adjunct) of Comparative Medicine

Research Interests:Pharmakokinetics; Emerging Therapeutics; Ophthalmology; Gene Therapy

Ifat Levy

Assistant Professor of Comparative Medicine and of Neurobiology

Research Interests:Decision-making; Value; Reward; Risk; Ambiguity; Functional MRI

James Macy, Jr

Professor of Comparative Medicine
Vice Chairman for Clinical Affairs, Comparative Medicine
Attending Veterinarian
Director, Yale Animal Resources Center

Research Interests:Pathogenesis; Prevention of mouse parvovirus infection; Laboratory Animal Medicine

James McGrath

Research Scientist in Comparative Medicine, in Genetics and in Pediatrics

Research Interests:Developmental Genetics; Genetic Imprinting; Embryogenesis; Spermatogenesis

Clinical Interests:Clinical Genetics; Dysmorphology; Cardiac Genetics

Timothy Nottoli

Research Scientist in Comparative Medicine
Co-director, Animal Genomics Services

Research Interests:Developmental Genetics; Animal Genomics; Gene Targeting and Transgenic Technology; Stem Cell Biology

Matthew Rodeheffer

Assistant Professor of Comparative Medicine and of Molecular, Cellular, and Developmental Biology

Research Interests:Genomics; Stem Cells

Jodi Scholz

Assistant Professor of Comparative Medicine

Research Interests:Environmental Enrichment; Laboratory Animal Medicine

Mark Sleeman

Professor (Adjunct) of Comparative Medicine

Research Interests:Physiology; Genomics

Peter Smith

Associate Professor of Comparative Medicine
Director, Residency Training Program

Research Interests:Epidemiology of rodent Infectious diseases; Laboratory Animal Medicine

Steven Wilson

Assistant Professor of Comparative Medicine

Research Interests:Virology and vaccine production; Laboratory Animal Medicine

Xiaoyong Yang

Assistant Professor of Comparative Medicine and of Cellular and Molecular Physiology

Research Interests:Nutrient Sensing; Circadian Rhythms; Metabolism; O-GlcNAc Modification; Nuclear Receptors; Diabetes; Cancer; Aging; Systems Biology

Gang-Qing Yao

Research Scientist in Comparative Medicine
Director, Vector Design and Engineering Service

Research Interests:Molecular Biology of Bone Metabolism; Bone Metabolism; Endocrine effects on bone loss. Dr. Yao’s research interest focuses on cellular and molecular mechanisms of Colony Stimulating Factor-1 isoforms in bone. Selective deletion of the isoform in vivo is being pursued to better define their separate roles. The lab also provides a complete vector design and construction for knockout and knockin mice, as well as transgenic mice.

Caroline Zeiss

Professor of Comparative Medicine and Associate Professor of Ophthalmology and Visual Science
Director, Mouse Research Pathology Service
Unit Chief, Pathology

Research Interests:Molecular and cellular pathogenesis of retinal degeneration; neurobiology of movement disorders; phenotypes of genetically engineered mice; evolutionary biology of the eye; Veterinary Pathology; Mouse Phenotyping; Ocular pathology with emphasis on photoreceptor disorders; Neuroanatomy of age-related gait disorders; Signal transduction events during neuronal death; Comparative pathology with emphasis on murine neuroanatomy; Phenotying genetically altered rodents