Cellular & Molecular Physiology Faculty

Caplan, Michael J

Chair

Research Interests:Ion pumps in polarized epithelia; Sorting and function

Addy, Nii Antie

Research Interests:Neurobiology of addiction; In vivo electrochemistry; Behavioral pharmacology; Systems neuroscience; Neurotransmission; Signal transduction

Ameen, Nadia Annitia

Research Interests:Apical endocytosis and exocytosis; Protein traffic; Secretory diarrhea; Cystic fibrosis

Aronson, Peter S.

Research Interests:Urinary electrolyte excretion; Cell membrane ion exchangers; Proximal tubule

Clinical Interests:Electrolyte and acid-base disorders; kidney stones

Bagriantsev, Slav

Research Interests:Sensory physiology; Biophysics; Biochemistry; Neuroscience; Electrophysiology; Polymodal ion channels; Temperature-sensitive ion channels; Mechanosensitive ion channels; Two-pore potassium channels; Ion channel pharmacology

Bordey, Angelique

Research Interests:Neurogenesis; stem cells; mTOR; Neural stem cell; Cognitive functions; autism

Clinical Interests:Tuberous Sclerosis Complex, Autism, Neurodevelopmental disorder

Boulpaep, Emile Louis Jean Bapti

Research Interests:Electrical properties of membrane proteins in plasma membranes and junctions of renal tubule cells

Brown, Thomas H

Research Interests:Neurobiological mechanism of learning and memory.

Canessa, Cecilia

Research Interests:Renal Function; Epithelial Sodium Channels

Cantley, Lloyd Garnet

Research Interests:Nephrology; Acute Kidney Injury; Physiology and integrative medical biology; Epithelial cell migration and morphogenesis; Epithelial cell adhesion; Migration; Branching tubulogenesis

Clinical Interests:Glomerulonephritis; vasculitis; electrolyte disorders

Chandler, W.

Research Interests:Cell Physiology, Electrophysiology, Human Physiology, Muscle Structure or Function, Calcium, Charge Movement, Excitation-contraction Coupling, Muscle, Sarcoplasmic Reticulum

Cohen, Lawrence Baruch

Research Interests:Brain; Central Nervous System; Neurons; Vertebrate Physiology; Olfaction; Olfactory Bulb; Protein Sensors of Voltage and Calcium

Demb, Jonathan B.

Research Interests:Neuroscience; Functional circuitry of the retina; Cellular basis of visual adaptation; Neural plasticity; Mechanisms of retinal disease

Egan, Marie E

Research Interests:Cystic fibrosis clinical studies; Cystic fibrosis basic science research (ion transport, Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) function); Cystic fibrosis translational research studies (strategies to bypass the basic defect)

Clinical Interests:Acute and chronic respiratory diseases; Asthma; Cystic fibrosis; Bronchopulmonary Dysplasia; Pneumonia; Congenital anomalies; Flexible bronchoscopy; Chronic ventilation; Sleep/sleep studies

Ehrlich, Barbara E

Research Interests:Intracellular calcium regulation

Eichmann, Anne

Research Interests:Vascular development and angiogenesis; Guidance of vascular patterning; Tip cells; Axonal growth cones; Vascular growth factors in the nervous system

Forbush, Biff

Research Interests:Membrane Proteins; Epithelial Transport; Ion Transport; Na-K-Cl Cotransporter; Nerve Cells; Muscle Cells

Geibel, John P

Research Interests:Gastric Acid Secretion; Colonic Fluid Transport; Renal Physiology; Intracellular Ion Activity Measurements; Calcium Sensing Receptor; Diarrheal disease; electrophysiology; CFTR; AMPKinase volume regulation

Gracheva, Elena

Research Interests:Sensory physiology; Molecular adaptations; Hibernation; Thermoregulation; Ion channels; Neuroscience

Kaczmarek, Leonard Konrad

Research Interests:Neuroscience; Learning and memory; Ion channels

Karatekin, Erdem

Research Interests:Membrane fusion; Exocytosis; Secretory vesicle dynamics; Fluorescence microscopy; Image analysis; Microfluidics; Supported bilayers; Proteoliposomes

Kibbey, Richard Glenn

Research Interests:Mechanisms of insulin secretion by beta-cells; Pathogenesis of beta-cell exhaustion in Type 2 Diabetes Mellitus; Mitochondria

Clinical Interests:Diabetes

Lister, George

Clinical Interests:Critical Care Medicine; Post-operative Care; Respiratory Failure

Nitabach, Michael N

Research Interests:Neurophysiology; Molecular genetics; Systems Physiology; Animal Behavior

Pieribone, Vincent Allen

Research Interests:Neurophysiology; Neurotransmission; Voltage and calcium imaging; Sensory physiology; Drug development; Coral biology; Fluorescent proteins

Preisig, Patricia Ann

Research Interests:Elucidation of the acid-activated pathway that mediates the physiological response of the renal proximal tubule to the need for the kidney to excrete acid

Rinehart, Jesse

Research Interests:Physiological Systems; Protein Phosphorylation; Cell Signaling; Phosphoproteomics; Protein Engineering; Ion Transport; Synthetic Biology; Translational Research

Saltzman, W. Mark

Research Interests:Bio-compatible polymers, drug delivery systems

Santos-Sacchi, Joseph

Research Interests:Mammalian inner ear

Shulman, Gerald I

Research Interests:Cellular and molecular mechanisms responsible for insulin resistance.

Clinical Interests:Diabetes

Sigworth, Frederick J.

Research Interests:Cell Physiology; Electron Microscopy; Electrophysiology; Ion Channel; Mathematical Model; Patch Clamp; Potassium Channel; Protein Structure; Sodium Channel; Voltage Gated Channel; Xenopus Oocyte

Singh, Satinder Kaur

Research Interests:Chemical neurotransmission; Neuropsychiatric disease; Epilepsy; Neuropharmacology; Biogenic amine; Gamma-aminobutyric acid; Neurotransmitter transporter; Antidepressant; Structural neurobiology; X-ray crystallography; Transporter kinetics

Slayman, Carolyn Walch

Research Interests:Genetics of Ion Transport

Slayman, Clifford L.

Research Interests:Charge-dependent Transport; Proton Pumps; Potassium channels; Ribosomally Synthesized AntiMicrobial Peptides (RAMPs)

Thoreen, Carson

Research Interests:Growth control; RNA; Translation; Cancer biology; Signaling; Biochemistry; Bioinformatics; Metabolism

Tomita, Susumu

Research Interests:Synaptic transmission; Brain; Biochemistry; Molecular biology; Immunocytochemistry; Gene-targeted animals; Electrophysiology

Wang, Tong

Research Interests:Kidney tubule transport; Electrolyte and acid-base balance; Transgenic animal models and human disease

Wright, Fred Smith

Research Interests:Renal Physiology

Yang, Xiaoyong

Research Interests:Nutrient Sensing; Cell Signaling; Circadian Rhythm; Post-translational Modifications; Metabolic Physiology; Diabetes; Cancer; Aging; Systems Biology

Young, Lawrence Howard

Research Interests:Myocardial ischemia; Metabolic adaptation to hypoxic stress; Cardio-protection; Cardiomyopathy; LKB1-AMPK pathway; Diabetes

Clinical Interests:Clinical cardiology; angina; diabetes; heart disease; valvular heart disease: HHT and heart disease

Zecevic, Dejan P

Research Interests:Physiology of axons, dendrites and dendritic spines; Input-output function of individual nerve cells; Voltage sensitive dyes; Optical recording methods

Zenisek, David

Research Interests:Physiology and cell biology of the presynaptic terminal; Retinal Bipolar Neuron; Synaptic Terminal; Synaptic Ribbons; Vesicle Transport; Exocytosis; Endocytosis

Zhou, Z. Jimmy

Research Interests:physiology and development of the mammalian retina under normal and pathological conditions; organization and function of retinal synapses and circuits; mechanisms of retinal diseases