Clara Abraham MD

Associate Professor of Medicine (Digestive Diseases)

Departments & Organizations

Yale Medical Group

Internal Medicine: Digestive Diseases: Inflammatory Bowel Disease Program: IBD - Gastroenterology - AdultLiver Center

Pediatric IBD Program

Research Interests

Regulation of the intestinal immune system; T cell trafficking and activation; genetics and immunobiology of inflammatory bowel disease more...

Education

• BS, University of Illinois at Urbana-Champaign, 1985
• M.D., University of Chicago Pritzker School of Medicine, 1989

Selected Publications

• Hedl M and Abraham C. Nod2-induced autocrine IL-1 alters signaling by ERK and p38 to differentially regulate secretion of inflammatory cytokines. Gastroenterology. epub, 9/8/2012.
• Huber S, Gagliani N, Zenewicz LA, Huber FJ, Hedl M, Zhang W, O’Connor W, Murphy AJ, Valenzuela DM, Yancopoulos GD, Booth CJ, Cho JH, Ouyang W, Abraham C, Flavell RA. The IL-22—IL-22BP axis is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature. (in press)
• Hedl M and Abraham C. IRF5 Risk Polymorphisms Contribute to Inter-Individual Variance in Pattern-Recognition Receptor-Mediated Cytokine Secretion in Human Monocyte-Derived Cells. J Immunol, 188:5348-5356, 2012.

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