Christopher H Van Dyck, MD

Professor of Psychiatry, Neurology, and Neurobiology; Director, Alzheimer's Disease Research Unit

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Contact Info

Christopher H Van Dyck, MD
Patient Care Locations
Yale Alzheimer's Disease Research Unit1 Church Street, Ste Suite 600
New Haven, CT 06510
874 Howard Avenue
New Haven, CT 06519
Mailing Address
Alzheimer's Disease Research UnitYale University School of Medicine
One Church Street

New Haven, CT 06510

Curriculum Vitae

Alzheimer's Disease Research Unit

Research Image 2

Frequency of psychosis by ApoE e4 carrier status and dementia severity. Mini Mental State Examination (MMSE) score was used to classify AD patients as mild (MMSE>19, n=103), moderate (MMSE=12-19, n=121), or severe (MMSE<12, n=42). Separate multiple logistic regression analyses were performed for each severity category, with presence of psychosis as dependent variable and the following independent variables (in addition to e4 carrier status): age, sex, educational attainment, and MMSE. *Only at the severe stage was the presence of e4 significantly associated with psychosis (odds ratio [OR]=16.61, 95% CI=2.11-130.51, P=.008). (From Zdanys KF , et al. 2007.)