Charles Ryan Wira, MD

Associate Professor Term; Liaison, Yale-New Haven Stroke Program

Departments & Organizations

Emergency Medicine: York Street

Faculty Research

Stroke Center

Yale Medicine

Office of Cooperative Research


Dr. Wira is board certified in Internal Medicine and Emergency Medicine. His scholarly pursuits are related to cardiac arrest, sepsis and stroke. He has performed cardiac arrest hypothermia studies in animal models that changed the 2010 AHA guidelines reccomending that vasoactive medications may now be administered in this extreme form of cardiac arrest. He was a member of the Early Goal Directed Collaborative group at Henry Ford Hospital in Detroit, MI performing clinical research on septic patients, and currently has multiple projects risk stratifying patients with severe sepsis. In stroke, he is a site co-investigator on NIH funded studies evaluating albumin and induced hypothermia in ischemic stroke patients, and industry funded trials evaluating extended windows for novel thrombolytics. He is a lead investigator on several stroke system studies funded by the AHA/ASA. A unique area of interest is the myocardial and hemodynamic complications in acute stroke patients.

Dr. Wira is currently the first Emergency Physician to serve as Chair of the Northeast Cerebrovascular Consortium (NECC, the northeast AHA/ASA region), he is also co-founder of the 2013-14 State of Connecticut Stroke Taskforce. He is a member of the Neurological Emergencies SAEM interest group and has been a member of the Emergency Critical Care Section of the Society of Critical Care Medicine. Dr. Wira is a peer reviewer for Academic Emergency Medicine, Emedicine, Critical Care Medicine, Medscape, Internal and Emergency Medicine, and Critical Care. He has extensive involvement in teaching medical students and residents. He is a faculty advisor to several residents for their scholarly projects and has served as thesis advisor to a number of medical students.

Education & Training

MD Dartmouth School of Medicine (2000)
BS University of New Hampshire (1993)
Resident Henry Ford Hospital

Honors & Recognition

  • 2011 Residency Teacher of the Year--Yale DEMYale DEM Residents (2011)

  • Co-Chair of the Acute Stroke SectionNECC/AHA/ASA

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Contact Info

Charles Ryan Wira, MD
Patient Care Locations
Yale Emergency MedicineYale New Haven Hospital
20 York Street, Ste South Pavilion Suite 218

New Haven, CT 06510
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Yale Emergency MedicineYale New Haven Shoreline Medical Center
111 Goose Lane

Guilford, CT 06437
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Mailing Address
PO Box 208053
New Haven, CT 06520-8053