Cell Biology Faculty

Baddeley, David

Research Interests: Microscopy, super-resolution

Bewersdorf, Joerg

Research Interests: Super-resolution fluorescence microscopy

Bogan, Jonathan S

Research Interests: Protein trafficking; Ubiquitin-like modification; Cell structure; Insulin signaling; Type 2 diabetes; Metabolic diseases

Clinical Interests: General endocrinology; diabetes

Burd, Chris

Research Interests: organelle biogenesis, endocytosis, secretion, phosphoinositide signaling

Calderwood, David A.

Research Interests: Integrin; Cell adhesion; Cell migration; Cytoskeleton; Structural biology

Caplan, Michael J

Research Interests: Ion pumps in polarized epithelia; Sorting and function

Carroll, Topher

Research Interests: Epigenetics; Chromosomes; Chromatin; Gene expression; Nuclear Organization; Nuclear Membrane;

Colón-Ramos, Daniel Alfonso

Research Interests: Neural connectivity; Brain; Nematode C. elegans

Cooley, Lynn

Research Interests: Molecular Genetics of Drosophila Oogenesis; Actin Cytoskeleton Regulation; Drosophila; Oogenesis; Ring Canal; Ovarian Muscle Function

Cresswell, Peter

Research Interests: Molecular mechanisms of antigen processing; Assembly and intracellular transport of CD1 molecules, Class I and Class II MHC molecules; Effector functions; mechanisms of action of interferon-induced proteins; Viral immunity

De Camilli, Pietro

Research Interests: Synapses; Membrane Traffic; Endocytosis; Clathrin; Dynamin; Phosphoinositides; Lipid Metabolism; Lowe Syndrome; Bar Proteins; Neurodegeneration; Membrane Contact Sites

Clinical Interests: N/A

Dufresne, Eric Robert

Research Interests: Mechanics of cells and tissues. Self-assembly of proteins, membranes and cells. Soft matter physics.

Ferguson, Shawn Michael

Research Interests: Lysosomes; Membrane traffic; Energy homeostasis; Nutrient homeostasis; Transcription factor; Signaling; Neurodegeneration; Neuronal ceroid lipofuscinosis; Genetics

Galan, Jorge E

Research Interests: Microbial Pathogenesis; Host/pathogen interaction

Gorelick, Fred

Research Interests: Exocrine pancreas; Pancreatitis; Intracellular proteolysis; Vacuolar ATPase; AMPK; Protein kinase C

Guo, Shangqin

Research Interests: Cell fate control; Reprogramming; Hematopoietic stem and progenitors; Leukemogenesis; Cell cycle; live-cell imaging

Hashimoto, Carl

Research Interests: Proteolysis; Serpins; Intercellular signaling; Morphogenesis; Disease modeling; Drosophila molecular genetics

Jamieson, James Douglas

Research Interests: Endocrine pancreas; Secretory pathways; Lung development

King, Megan C.

Research Interests: Microtubules; Nucleus; Nuclear envelope; DNA repair; Cellular mechanics; Telomere biology

Krause, Diane S

Research Interests: Bone Marrow Transplantation; Stem Cells; Cell and Molecular Hematology; Leukemia

Clinical Interests: Transfusion medicine; stem cell transplantation; stem cell processing; apheresis

Lin, Chenxiang

Research Interests: Engineering DNA-nanostructure-based molecular tools for biological study

Lin, Haifan

Research Interests: Stem cell RNA-mediated epigenetic programming, post-transcriptional regulation

Clinical Interests: Stem cell research

Lusk, Patrick

Research Interests: Nuclear pore complex; Nuclear periphery; Membrane proteins; Chromatin structure

Marchesi, Vincent T

Research Interests: Pathogenesis of Alzheimer's disease; Neurodegeneration; Amyloid abeta metabolism; Auto-antibodies; Protein-folding

Clinical Interests: Alzheimer's disease; adult neurodegeneration

Mariappan, Malaiyalam

Research Interests: Unfolded Protein Response (UPR); Endoplasmic Reticulum; Protein Translocation and Insertion; ER stress response; Misfolded Proteins; Protein Quality Control

Melia, Thomas

Research Interests: Macroautophagy; Autophagy

Mooseker, Mark S

Research Interests: The cytoskeleton. Epithelial cell biology. molecular motors

Nathanson, Michael Harris

Research Interests: Mechanisms and effects of calcium signals in polarized epithelia; Effect of spatial organization of calcium signals on organ function regulation; Factors that organize Ca2+ waves in hepatocytes; Organization and effects of Ca2+ waves in cholangiocytes; Mechanisms and effects of Ca2+ signals in the nucleus

Clinical Interests: Inpatient care related to hepatology; end stage liver disease, and gastroenterology; Advanced endoscopic imaging techniques; endomicroscopy.

Pollard, Thomas Dean

Research Interests: Cytokinesis; cellular motility; role of actin filaments and myosin motors

Rothman, James E

Research Interests: Elucidating the underlying mechanisms of vesicular transport within cells; Secretion of hormones and neurotransmitters

Schwartz, Martin A

Research Interests: Integrin signaling; Mechanotransduction; Atherosclerosis; Vascular remodeling; Heart disease; Extracellular matrix; Cell adhesion; Cytoskeleton; Cell-cell junctions; Fluid shear stress

Simons, Michael

Research Interests: Angiogenesis; Arteriogenesis; Lymphangiogenesis; Endothelial Signaling; tyrosine kinase signaling; vascular development; FGF; VEGF; endocytosis

Clinical Interests: Coronary artery disease; acute myocardial infarction

Toomre, Derek K.

Research Interests: Cell Biology; Exocytosis; Endocytosis; Membrane Traffic; Tethering; Microscopy; Live Cell Imaging; TIRFM; Single molecule

Vignery, Agnès M C

Research Interests: Differentiation mechanism of osteoblasts; Fusion mechanism of macrophages

Wolin, Sandra L

Research Interests: Noncoding RNAs; RNA surveillance; RNA damage; Autoimmune disease; Environmental stress

Yao, Jie

Research Interests: Transcription regulation; Chromatin; Nuclear periphery; Nuclear compartmentalization; Protein dynamics; Cellular biophysics and imaging

Zhang, Yongli

Research Interests: Single-molecule biophysics and biochemistry; Optical tweezers; ATP-dependent chromatin remodeling; SNAREs; Membrane fusion; Membrane fission; Dynamin