Basmah Safdar MD, FACEP

Assistant Professor of Emergency Medicine; Co-Chair, Chest Pain Center; Director, YNHH Women's Heart Program

Research Interests

Clinical research; chest pain center; women and cardiovascular disease; gender research; cardiac biomakers; cardiovascular disease; coronary risk factors; depression; disparities; education; chest pain in a multidimensional model; pain; perception; women's health; microvessel disease; endothelial reactivity


Research Summary

Dr. Safdar's research interests focus on women’s health, in particular gender disparities in cardiovascular health and a multisystem approach to pain management in the Emergency Department. Dr. Safdar serves as the Medical Director of the Yale New Haven Hospital Women’s Heart Program, a comprehensive community awareness program that aims to improve knowledge of women about heart disease. Dr. Safdar is also the Director of the Chest Pain Center.

She has served as the site PI for a MIDAS (Myeloperoxidase in the Diagnosis of Acute Coronary Syndrome) study involving ED patients. She has presented her work on perception of ED patients regarding CHD risk factors at regional and national forums. Dr. Safdar has won the Best Clinical Science Research Award 2005 for resident category by Society of Academic Emergency Medicine (SAEM). Dr. Safdar was the site PI for a PEMI (Pain and Emergency Medicine Initiative) study, a 20 center clinical epidemiological and outcome study of patients presenting with pain to the ED. She serves on the PEMI interest group at SAEM and is on the Editorial Board of EM Painline, a web based resource aimed at providing EM researchers and clinicians with information to improve EM pain-related research and practice. Dr. Safdar supervises the cardiovascular curriculum for the Yale EM residents and is actively involved in Yale medical student education. She is also appointed as Fellow in Yale Branford College and serves as an advisor for the undergraduates.


Selected Publications

  • McGregor AJ, Greenberg M, Safdar B, Seigel T, Hendrickson R, Poznanski S, Davenport M, Miner J, Choo EK (2013). Focusing a gender lens on emergency medicine research: 2012 update. Acad Emerg Med. 2013 Mar;20(3):313-20.
  • Safdar B, Lichtman JH, D'Onofrio G (2012). Sex and the CT: An Evolving Story of the Heart. Acad Emerg Med. 2012 Feb;19(2):197-200. doi: 10.1111/j.1553-2712.2011.01288.x.
  • Safdar B, McGregor AJ, McKee SA, Ali A, Radulescu R, Himelfarb NT, Klein MR, Mazure CM (2011). Inclusion of gender in emergency medicine research. Academic Emergency Medicine. Feb;18(2):e1-4.
  • Peacock WF, Diercks D, Hollander J, Singer A, Birkhah R, Shapiro N, Glynn T, Nowack R, Safdar B, Miller C, Bewandrowski E, Nagurney J (on behalf of the MIDAS Investigators) (2011). Myeloperoxidase in the Diagnosis of Acute Coronary Syndromes: The Importance of Spectrum. Am Heart J. Nov;162(5):893-9.
  • Diercks D, Peacock WF, Hollander J, Singer A, Birkhah R, Shapiro N, Glynn T, Nowack R, Safdar B, Miller C, Bewandrowski E, Nagurney J (on behalf of the MIDAS Investigators)(2011). Diagnostic Accuracy of a Contemporary TnI Assay for Myocardial Infarction at 6 hours After Presentation in Early Presenters to the Emergency Department with Chest Pain. Am Heart J. 2012 Jan;163(1):74-80.e4.
  • Safdar B, Foody JM, D’Onofrio G. (2010). Depression as Modifiable Coronary Risk factor in the Emergency Department Chest Pain Observation Unit. Critical Care Pathways in Cardiology. Volume 9, Number 2, June 2010.
  • Heins A, Homel P, Safdar B, Todd K.(2010). Physician Race/Ethnicity Predicts Successful Emergency Department Analgesia. Journal of Pain, 2010 Apr 9.
  • Safdar B, DeSandre P, Heins A, et al.(2009) Impact of Physician and Patient Gender on Pain Management in the Emergency Department – A Multi-Center study. Pain Medicine. Mar 2009; 10(2):364-72.
  • Rao VS, Safdar B, Lee V (2008) Improvements in Time to Reperfusion: Women Have an Advantage. Critical Pathways in Cardiology
  • Safdar B (2008) "Gender Differences in Patient and Emergency Physician Perceived Risk of Heart Disease in an ED Chest Pain Center", American Conference of Emergency Physicians Conference, Chicago, IL.

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