Arthur L Horwich MD

Sterling Professor of Genetics and Professor of Pediatrics; and Investigator HHMI

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Biochemistry, Biophysics and Structural Biology

Kavli Institute for Neuroscience

Pediatrics

Genetics


Research Interests

Chaperones in protein folding; ALS (Lou Gehrig's Disease) more...


Education

  • M.D., Brown University, 1975

Selected Publications

  • 1. Bandyopadhyay, U., Cotney, J., Nagy, M., Oh, S., Leng, J., Mahajan, M., Mane, S., Fenton, W.A., Noonan, J., and Horwich, A.L. (2013) RNA-seq profile of spinal cord motor neurons from a presymptomatic SOD1 ALS mouse. PLoS ONE. http://dx.plos.orgt/10.1371/journal.pone.0053575
  • Song, Y., Nagy, M., Ni, W., Tyagi, N., Fenton, W.A., Lopez-Giraldez, F., Overton, J., Horwich, A.L., and Brady, S.T. (2013) Molecular chaperone Hsp110 rescues a vesicle transport defect produced by an ALS-associated mutant SOD1 protein in squid axoplasm. Proc. Natl. Acad. Sci. USA 110, 5428-5433.
  • Elad, N., Farr, G.W., Clare, D.K., Orolova, E.V., Horwich, A.L., and Saibil, H.R. (2007). Topologies of a substrate protein bound to the chaperonin GroEL. Mol. Cell 26, 415-426.

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