Andrew Wang, MD/PhD, AB

Associate Research Scientist

Research Organizations


Extensive Research Description

ABIM Research Pathway Resident, Yale Internal Medicine Traditional Residency Program

  1. Daudin JB, Monnet D, Kavian N, Espy C, Wang A, Chéreau C, Goulvestre C, Omri S, Brézin A, Weill B, Batteux F, Nicco C. Protective effect of pristane on experimental autoimmune uveitis. Immunol Lett. 2011 Dec 30;141(1):83-93. Epub 2011 Aug 27.
  2. Wang A, Batteux F, Wakeland EK. The role of SLAM/CD2 polymorphisms in systemic autoimmunity. Curr Opin Immunol. 2010 Dec;22(6):706-14. Epub 2010 Nov 18.
  3. Kavian N, Servettaz A, Mongaret C, Wang A, Nicco C, Chéreau C, Grange P, Vuiblet V, Birembaut P, Diebold MD, Weill B, Dupin N, Batteux F. Targeting ADAM-17/notch signaling abrogates the development of systemic sclerosis in a murine model. Arthritis Rheum. 2010 Nov;62(11):3477-87. doi: 10.1002/art.27626.
  4. Servettaz A, Kavian N, Nicco C, Deveaux V, Chéreau C, Wang A, Zimmer A, Lotersztajn S, Weill B, Batteux F. Targeting the cannabinoid pathway limits the development of fibrosis and autoimmunity in a mouse model of systemic sclerosis. Am J Pathol. 2010 Jul;177(1):187-96. Epub 2010 May 27.
  5. Wang A, Guilpain P, Chong BF, Chouzenoux S, Guillevin L, Du Y, Zhou XJ, Lin F, Fairhurst AM, Boudreaux C, Roux C, Wakeland EK, Davis LS, Batteux F, Mohan C. Dysregulated expression of CXCR4/CXCL12 in subsets of patients with systemic lupus erythematosus. Arthritis Rheum. 2010 Nov;62(11):3436-46. doi: 10.1002/art.27685
  6. Wang A, Wakeland EW, Mohan C. “Genetic susceptibility to kidney disease as a consequence of systemic autoimmunity.” Genetic Diseases of the Kidney. Ed. Richard P. Lifton, Stefan Somlo, Gerhard Giebisch and Donald W. Seldin. Elsevier: New York, 2009. Chapter 44
  7. Fairhurst AM, Xie C, Fu Y, Wang A, Boudreaux C, Zhou XJ, Cibotti R, Coyle A, Connolly JE, Wakeland EK, Mohan C. Type I interferons produced by resident renal cells may promote end-organ disease in autoantibody-mediated glomerulonephritis. J Immunol. 2009 Nov 15;183(10):6831-8. Epub 2009 Oct 28.
  8. Vallet C, Pons-Catalano C, Mandelcwajg A, Wang A, Raymond J, Lebon P, Gendrel D. Human bocavirus: a cause of severe asthma exacerbation in children. J Pediatr. 2009 Aug;155(2):286-8.
  9. Wang A, Fairhurst AM, Tus K, Subramanian S, Liu Y, Lin F, Igarashi P, Zhou XJ, Batteux F, Wong D, Wakeland EK, Mohan C. CXCR4/CXCL12 hyperexpression plays a pivotal role in the pathogenesis of lupus. J Immunol. 2009 Apr 1;182(7):4448-58.
  10. Fairhurst AM, Hwang SH, Wang A, Tian XH, Boudreaux C, Zhou XJ, Casco J, Li QZ, Connolly JE, Wakeland EK. Yaa autoimmune phenotypes are conferred by overexpression of TLR7. Eur J Immunol. 2008 Jul;38(7):1971-8.
  11. Young JA, Becker AM, Medeiros JJ, Shapiro VS, Wang A, Farrar JD, Quill TA, Hooft van Huijsduijnen R, van Oers NS. The protein tyrosine phosphatase PTPN4/PTP-MEG1, an enzyme capable of dephosphorylating the TCR ITAMs and regulating NF-kappaB, is dispensable for T cell development and/or T cell effector functions. Mol Immunol. 2008 Aug;45(14):3756-66. Epub 2008 Jul 9.
  12. Fairhurst AM, Mathian A, Connolly JE, Wang A, Gray HF, George TA, Boudreaux CD, Zhou XJ, Li QZ, Koutouzov S, Banchereau J, Wakeland EK. Systemic IFN-alpha drives kidney nephritis in B6.Sle123 mice. Eur J Immunol. 2008 Jul;38(7):1948-60.
  13. Wang A. The Roles of Ly108, the Genetic Susceptibility Loci Sle3, and CXCR4/CXCL12 in Systemic Lupus Erythematosus. Doctorate Thesis. Available through UTSW Library System. 2008
  14. Wang A, Mohan C. Identification of the Yaa lupus gene as a Tlr-7 gene duplication evemt. Future Rheumatology. 2006 Oct: 1(5): 563-565.
  15. Subramanian S, Tus K, Li QZ, Wang A, Tian XH, Zhou J, Liang C, Bartov G, McDaniel LD, Zhou XJ, Schultz RA, Wakeland EK. A Tlr7 translocation accelerates systemic autoimmunity in murine lupus. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9970-5. Epub 2006 Jun 15.
  16. Tran TM, Satumtira N, Dorris ML, May E, Wang A, Furuta E, Taurog JD. HLA-B27 in transgenic rats forms disulfide-linked heavy chain oligomers and multimers that bind to the chaperone BiP. J Immunol. 2004 Apr 15;172(8):5110-9.
  17. Wang A. The Role of Complement C4 in SLE. Available through Harvard Oress. 2004
  18. Zhou X, Tan FK, Reveille JD, Wallis D, Milewicz DM, Ahn C, Wang A, Arnett FC. Association of novel polymorphisms with the expression of SPARC in normal fibroblasts and with susceptibility to scleroderma. Arthritis Rheum. 2002 Nov;46(11):2990-9.

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