Liana Fraenkel, MD, MPH

Professor of Medicine (Rheumatology); Section Chief of Rheumatology, CT Veterans Administration Medical Center

Departments & Organizations

Internal Medicine: Liver Center | Rheumatology: Rheumatology Leadership

Faculty Research

Yale Medicine

Office of Cooperative Research


Dr. Fraenkel’s research interests lie in applying scientifically rigorous approaches to better understand and improve both patient and physician decision making. Her efforts have resulted in a series of papers describing the use and value of conjoint analysis to ascertain patient treatment preferences across a range of sociodemographic groups and diseases, and customization of the original software program to improve use with patients. Dr. Fraenkel’s work has also led to new insights into decision making which have important clinical implications. For example, using conjoint analysis, she has demonstrated that rheumatoid arthritis patient preferences for more aggressive treatment with disease modifying antirheumatic drugs differ by race, with Black patients preferring less aggressive treatment compared to White patients with similar disease severity. These results may help explain the disparity in utilization of newer riskier drugs in minority patients. Dr. Fraenkel is currently working on developing web-based decision support tools, based on Fuzzy Trace theory, for patients facing decision involving medications with significant risks of toxicity.

van Hulst L; Kievit W Bommel R; van Riel PL, Fraenkel L. Rheumatoid arthritis patients and rheumatologists approach the decision to escalate care differently. Arthritis Care Res 2011;63:1407-14.
Fraenkel L, Falzer P, Fried TR, Kohler M, Peters E, Kerns R, Leventhal H. Measuring pain impact versus pain severity using a numeric rating scale. J Gen Intern Med 2012;27:555-60.

Fraenkel L, Peters E, Charpentier P, Olsen B, Errante L, Schoen RT, Reyna V. A decision tool to improve the quality of care in rheumatoid arthritis. Arthritis Care Res 2012; Mar 5. doi: 10.1002/acr.21657.

Education & Training

MPH Boston University (1997)
MD McGill University (1990)
BS McGill University (1986)
Fellow Boston University

Honors & Recognition

  • ACR Henry Kunkel Young Investigator AwardAmerican College of Rheumatology (2009)

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