Daniel Robert Goldstein MBBS

Professor of Medicine (Cardiology) and of Immunobiology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Immunology

Yale Medical Group

Office of Student ResearchVascular Biology and Therapeutics ProgramImmunobiology: HTIInternal Medicine: Cardiovascular Medicine: Yale Cardiovascular Research Center, Heart Failure & TransplantYale Center for Advanced Heart Failure, Mechanical Circulatory Support, and Heart TransplantationImmunology and Immunotherapy

Research Interests

Immunity in transplantation; Impact of aging on inflammation and immunity more...


  • M.B.B.S., University of London, 1992

Selected Publications

  • Song Y, Shen H, Du W and Goldstein DR. Inhibition of x-box binding protein 1 expression reduces tunicamycin-induced apoptosis in aged murine macrophages. Aging Cell 2013 (12): 794-801
  • Song Y, Shen H, Schenten D, Lee PJ and Goldstein DR. Aging enhances the basal production of IL-6 and CCL2 in vascular smooth muscle cells. Arteriosclerosis, Thrombosis and Vascular Biology, 2012 Jan;32(1):103-9
  • Shen H, Song Y, Colangelo C, Wu T, Bruce C, Scabia G, Maffei M and Goldstein DR. Haptoglobin activates innate immunity to enhance acute transplant rejection in mice The Journal of Clinical Investigation 2012, (122):383-387



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