Patrick G Gallagher MD

Professor of Pediatrics (Neonatology), of Genetics and of Pathology; Director, Yale Center for Blood Disorders; Director, Expression and Genomics Core, Yale Center of Excellence in Molecular Hematology

Departments & Organizations

Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development: Cytoskeleton and Cell Morphogenesis; Genetics and Genomics

Yale Medical Group

Stem Cell Center, Yale: Transcriptional Regulation of Stem and Progenitor Cells

Pathology: Surgical Pathology

Pediatrics: Neonatal-Perinatal Medicine: Newborn Special Care Unit

Genetics

Signal Transduction

Research Interests

Neonatal hematology; Erythropoiesis; Inherited abnormalities of the erythrocyte including metabolic, membrane, and hemoglobin disorders; Sickle cell disease; Hereditary spherocytosis; Elliptocytosis; Pyropoikilocytosis; Stomatocytosis more...

Education

• M.D., Northeastern Ohio University, 1985

Selected Publications

• Laflamme K, Owen AN, Devlin EE, Yang MQ, Wong C, Steiner LA, Garrett LJ, Elnitski L, Gallagher PG, Bodine DM.Functional analysis of a novel cis-acting regulatory region within the human ankyrin gene (ANK-1) promoter. Mol Cell Biol. 2010 Jul;30(14):3493-502. Epub 2010 May 17. PMID:20479128
• Li D, Harper SL, Tang HY, Maksimova Y, Gallagher PG, Speicher DW. A comprehensive model of the spectrin divalent tetramer binding region deduced using homology modeling and chemical cross-linking of a mini-spectrin. J Biol Chem. 2010 Sep 17;285(38):29535-45. Epub 2010 Jul 6.PMID: 20610390
• Yang MQ, Laflamme K, Gotea V, Joiner CH, Seidel NE, Wong C, Petrykowska HM, Lichtenberg J, Lee S, Welch L, Gallagher PG, Bodine DM, Elnitski L. Genome-wide detection of a TFIID localization element from an initial human disease mutation. Nucleic Acids Res. 2011 Mar;39(6):2175-87. Epub 2010 Nov 11.PMID: 21071415

more...