Joseph Edgar Craft MD

Paul B. Beeson Professor of Medicine (Rheumatology) and Professor of Immunobiology; Section Chief, Rheumatology; Program Director, Investigative Medicine; Paul B. Beeson Professor of Medicine

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Immunology | Molecular Medicine, Pharmacology, and Physiology

Yale Medical Group

Office of Student ResearchClinical Investigation, Yale Center for (YCCI): Educational Program: IMPCancer ImmunologyImmunobiology: HTIInternal Medicine: RheumatologyImmunology and Immunotherapy

Research Interests

Autoimmunity; Cytokines; Lupus; T Cell Differentiation; Tolerance more...


  • M.D., University of North Carolina, 1977

Selected Publications

  • Shulman Z, Gitlin AD, Weinstein JS, Lainez B, Esplugues E, Flavell RA, Craft J, Nuzzenzweig M. T follicular helper cell Ca2+ signaling during B cell selection in germinal centers. Science. 2014. 345:1058-1062.
  • Ray JP, Marshall HD, Laidlaw BJ, Staron MW, Kaech SM, Craft J. The Transcription Factor STAT3 and Type I Interferons Are Mutually Repressive Insulators for Differentiation of Follicular Helper and T Helper 1 Cells. 2014 Immunity 40:367-377. NIHMS 570364 [PMCID in process].
  • Laidlaw BJ, Zhang N, Marshall HD, Staron MM, Guan T, Hu Y, Cauley LS, Craft J*, Kaech SM*. CD4+ T cell help and transcription factor T-bet mediated repression of CD103 is critical for lung resident memory CD8+ T cell formation. Immunity (in press) (*co-senior and co-corresponding authors).



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