Pulmonary Laboratories & Research Groups

Pulmonary Labs A-J

Picking up test tubes

Chupp Laboratory

Our lab focuses on the Pathogenesis of airway diseases with a focus on asthma and asthma severity, the role of chitinases in the development and severity of asthma, and expression and genotype-phenotype relationships of novel inflammatory molecules. Read More...

Cohn Laboratory

Dr. Cohn's research focuses on airway inflammation. Read More...

Dela Cruz Laboratory

His laboratory focuses on two main research programs. (1) Studying the effects of cigarette smoke (CS) exposure in the pathogenesis of airway and lung diseases such as chronic obstructive pulmonary disease (COPD) using preclinical genetic mouse models and human biosamples. (2) Studying novel immune regulators in the lung during respiratory infections. Read More...

Gomez Laboratory

Gomez Laboratory examines the role of secondhand cigarette smoke in the transcriptome of the asthmatic airway. Computational biology of the lung. Translational informatics of lung disease. Read More...

Herzog Laboratory

The Herzog lab’s mission is to perform high quality translational studies aimed at elucidating common mechanism(s) of multiple forms of pulmonary fibrosis. Read More...

Pulmonary Labs K-Z

alt text

Kang Laboratory

Kang laboratory is focusing on the role(s) of mitochondrial dysfunction and immune dysregulation in the setting of smoking exposure such as those seen in patients with COPD and CS- and virus-associated disorders. Read More...

Koff Laboratory

Our research program focuses on elucidating airway epithelial signaling pathways that are important for inflammatory responses to pathogens. Read More...

Lee (Patty J.) Laboratory

Paty Lee Laboratory investigates mechanisms of lung injury and cytoprotection during oxidant stress. Specifically, we have focused on the lung endothelium as a central mediator of lung injury and repair responses. Read More...

Mannam Laboratory

Mannam laboratory is interested in determining the role of innate immune signaling pathways in sepsis and lung injury. Specifically, we are investigating the role of MKK3, a mitogen-activated protein kinase-signaling molecule, in the regulation of endothelial function and septic responses. Read More...

Takyar Laboratory

Takyar Laboratory research is focused on understanding the genetic and epigenetic basis of a variety of lung disease ranging form asthma to lung cancer. Read More...

Research Groups

ICU Research Working Group

The MICU Database and Biorepository was established in 2012 and currently is enrolling patients who are admitted to the medical ICU who are age 18 or older with ARDS, ALI, sepsis or other critical illness. Read More...

TIP Research Working Group

The TIP Research Group under the direction of Jonathan Puchalski, MD has established a database of all patients undergoing thoracic interventional procedures at Yale-New Haven Hospital. These procedures include diagnostic and therapeutic bronchoscopy, pleural procedures including pleurx catheter placement, pleuroscopy and thoracentesis as well as percutanous tracheostomies. Read More...

Sleep in ICU Research Group

We have examined the feasibility of using both polysomnography and actigraphy for measuring sleep in critically ill patients in our medical ICU. We are also examining the impact of noise, light and staff interruptions to sleep in our ICU. Read More...

Translational Lung Research Group (TLRP)

The mission of the Translational Lung Research Program (TLRP) is to enable high quality studies spanning the gap from bench to bedside and back again. Read More...