Jonathan Puchalski, MD

Associate Professor of Internal Medicine (Pulmonary, Critical Care and Sleep Medicine); Director, Interventional Pulmonology; Director, Interventional Pulmonary Fellowship

Research Organizations

Internal Medicine: Pulmonary, Critical Care & Sleep Medicine: TIP Research Working Group

Yale Cancer Center: Cancer Prevention and Control

Office of Cooperative Research

Research Summary

My research focuses on improving the diagnostic yield of bronchoscopic and pleural procedures, as well as the safety of these procedures. I have an extensive list of publications, including those advocating new techniques we have developed in our interventional pulmonary program.

Extensive Research Description

  1. Argento, AC, J Puchalski.Convex Probe EBUS for Centrally Located Parenchymal Lesions without a Bronchus Sign.Respiratory Medicine, 2016:116, 55-58.
  2. Bramley, K., Pisani M, Murphy T, Araujo K, Homer R and Puchalski J.Endobronchial Ultrasound-Guided Cautery-Assisted Transbronchial Forceps Biopsies:Safety and Sensitivity Relative to Transbronchial Needle Aspiration.Annals of Thoracic Surgery. 2016
  3. Ramaswamy, A, Homer R, Killam J, Pisani MA, Murphy TE, Araujo K, Puchalski J.Comparison of Transbronchial and Cryobiopsies in Evaluation of Diffuse Parenchymal Lung Disease.J Bronchology Interv Pulmonol. 2016; 23(1): 14-21.
  4. Ost, DE, Ernst, A, Lei X, Kovitz KL, Benzaquen S, Diaz-Mendoza J, Greenhill S, Toth J, Feller-Kopman D. Puchalski J, Baram D, Karunakara R, Jimenez CA, Filner JJ, Morice RC, Eapen GA, Michaud GC, Estrada-Y-Martin RM, Rafeq S, Grosu HB, Ray C, Gilbert CR, Yarmus LB, Simoff M; AQuIRE Bronchoscopy Registry.Diagnostic Yield and Complications of Bronchoscopy for Peripheral Lung Lesions:Results of the AQuIRE Registry.Am J Respir Crit Care Med. 2016; 193(1): 68-77
  5. Argento AC, Murphy TE, Pisani MA, Araujo KL, Puchalski J. Patient-Centered Outcomes Following Thoracentesis.Pleura. 2015.
  6. Rabach, L, Siegel M, Puchalski JT, et al.Use of the Blom Tracheotomy Tube with Suction Inner Cannula to Decontaminate Microorganisms from the Subglottic Space. A Proof of Concept.Ann Am Thorac Soc. 2015; 12(6): 859-63.
  7. DeBiasi EM, Pisani MA, Murphy TE, Araujo K, Kookoolis A, Argento AC, and Puchalski J.Mortality among patients with pleural effusion undergoing thoracentesis. Eur Respir J. 2015.

8. Goyal, G, Pisani, M, Murphy, T, Araujo, K and Puchalski, J. Advanced Diagnostic Bronchoscopy Using Conscious Sedation and the Laryngeal Nerve Block: Tolerability, Thoroughness and Diagnostic Yield. Lung, 2014.

9. Kookoolis, A, Puchalski, J, Murphy, T, Araujo, K and Pisani, M. Mortality of Hospitalized Patients with Pleural Effusions. Journal of Pulmonary & Respiratory Medicine, 2014.

10. Puchalski JT, Argento AC, Murphy TE, Araujo KLB, Pisani MA.The safety of thoracentesis in patients with uncorrected bleeding risk. Ann Am Thorac Soc. 2013.

11. Cai, G, Wong, R., Chhieng, D., Levy, Gl, Gettinger, S., Herbst, R. Puchalski, JT, Homer, R., and Hui, R.Identification of Epidermal Growth Factor Receptor Mutation, k-Ras Mutation, and EML4-ALK Translocation in the Cytological Specimens of Primary and Metastatic Lung Adenocarcinomas.Cancer Cytopathology.2013.doi: 10.1002/cncy.21288

12. Lee, H.J., Feller-Kopman, D, Shepherd, R. W., Almeida, F., Bechara, R., Berkowitz, D, Chawla, M., Folch, E., Gillespie, C., Haas, A., Lee, R., Majid, A, Malhotra, R., Musani, A., Puchalski, J., Sterman, D, Yarmus, L.Validation of an Interventional Pulmonary Examination. Chest, 2013; 143(6):1667-70.

13. Puchalski, J.T., Argento, A.C., Murphy, T.E., et al.Etiologies of Bilateral Pleural Effusions.Respiratory Medicine, 2013; 107(2): 284-91.

14. Puchalski JT, Argento AC, Murphy TE, Araujo KLB, Pisani MA.The safety of thoracentesis in patients with uncorrected bleeding risk. Ann Am Thorac Soc. 2013.In press.

15. Lee, H.J and Puchalski, J.¸Sterman, D.S. et al.Secondary Carina Y-Stent Placementfor Post-Lung-Transplant Bronchial Stenosis.Journal of Bronch and Interventional Pulmonology. 2012; 19(2):109-14.

Selected Publications

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Contact Info

Jonathan Puchalski, MD
Patient Care Locations
Winchester Chest ClinicFitkin Memorial Pavilion
789 Howard Avenue, Ste 2nd Floor

New Haven, CT 06519
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Yale Thoracic Oncology ProgramSmilow Cancer Hospital at Yale - New Haven
35 Park Street, Ste 4th Floor Multispecialty Care Center

New Haven, CT 06511
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Yale Pulmonary & Critical Care MedicineYale-New Haven Hospital
20 York Street

New Haven, CT 06510
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Mailing Address
15 York Street
New Haven, CT 06510

Curriculum Vitae

TIP Research Working Group