Clinical Trials

The Section of Pulmonary, Critical Care and Sleep Medicine (PCCSM) advances the research of pharmaceutical, biological and medical device products by developing collaborations between industry and academia. The Institute seeks to provide an efficient integration of academic expertise and industry clinical objectives. PCCSM offers its industry sponsors access to valuable scientific leadership, focused operational research functionality and analysis of high quality clinical trial data. As a leading provider of clinical trial services, PCCSM plays an important role in assessing new products that improve the quality of peoples’ lives.

Pending IRB approval.collapse

For more information, see the Center for Asthma and Airway Diseases (YCAAD).

collapse
For more information, see the Center for Sleep Medicine.collapse
Pending IRB approval.collapse

FG-3019-049 (Fibrogen): A Phase 2a, Open-Label, Single-Arm Study to Evaluate the Safety, Tolerability, and Efficacy of FG-3019 in Subjects with Idiopathic Pulmonary Fibrosis
Status: Active - Enrolling.
Read More... 

PANTHER (NHLBI / Duke): Evaluating the Effectiveness of Prednisone, Azathioprine, and N-acetylcysteine in People With Idiopathic Pulmonary Fibrosis
Status: Active - Enrolling.
Read More...

PIPF-012 (InterMune): An Open-Label Extension Study of the Long Term Safety of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Status: Active - Enrolling.
Read More...

PIPF-016 (Intermune): A Randomized, Double Blind, Placebo Controlled, Phase 3 Study of the Efficacy and Safety of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis
Status: Active - Enrolling.
Read More...

collapse
The MIND-USA Study: Modifying the Impact of ICU-Associated Neurological
Status: Active - Enrolling.
Read More...collapse

ASC01 - A Randomized, Double-Blind, Placebo-Controlled, Phase II Multicenter Trial of a Monoclonal Antibody to CD20 (Rituximab) for the Treatment of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH)
Status: Active - Enrolling.
Read More...

COMPASS2 - Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH)
Status: Active - Closed to Enrollment.
Read More...collapse

RENEW (PneumRx): Lung Volume Reduction Coil for Treatment in Patients With Emphysema (RENEW) Study.
Status: Active - Enrolling
Read More...

ASPIRE (Aeris): Study of the AeriSeal System for HyPerInflation Reduction in Emphysema (ASPIRE).
Status: Active - Enrolling
Read More...

ASAP (CareFusion/Duke): Impact of Aggressive Versus Standard Drainage Regimen Using a Long Term Indwelling Pleural Catheter on the Incidence of Auto-Pleurodesis in Patients With Malignant Pleural Effusions.
Status: Active - Enrolling
Read More...

collapse
ADX-0001 (Allegro): Airway Epithelium Gene Expression in the Diagnosis of Lung Cancer.
Status: Active - Closed to Enrollment
Read More...collapse
Pending IRB approval.collapse