ILD Publications

2024

Characterizing interstitial lung disease among patients with psoriasis: A cross-sectional analysis in the NIH All of Us Research Program.Shaw VR, Damsky W, Homer RJ, Cohen JM. Clin Exp Dermatol. 2024 Apr 15; 2024 Apr 15. PMID: 38618708.
Stem cell migration drives lung repair in living mice.Chioccioli M, Liu S, Magruder S, Tata A, Borriello L, McDonough JE, Konkimalla A, Kim SH, Nouws J, Gonzalez DG, Traub B, Ye X, Yang T, Entenberg DR, Krishnaswamy S, Hendry CE, Kaminski N, Tata PR, Sauler M. Dev Cell. 2024 Apr 8; 2024 Feb 19. PMID: 38377991.
"Rounding Third Base and Heading Home": Arthritis & Rheumatology in 2024.Solomon DH, Kaplan MJ, Nigrovic PA, Bucala R. Arthritis Rheumatol. 2024 Apr 4; 2024 Apr 4. PMID: 38572586.
A small molecule macrophage migration inhibitory factor agonist ameliorates age-related myocardial intolerance to ischemia-reperfusion insults via metabolic regulation.Wang H, Slotabec L, Didik S, Li Z, Leng L, Zhao B, Bucala R, Li J. Metabolism. 2024 Apr; 2024 Jan 15. PMID: 38232801.
Dedifferentiated early postnatal lung myofibroblasts redifferentiate in adult disease.Chandran RR, Adams TS, Kabir I, Gallardo-Vara E, Kaminski N, Gomperts BN, Greif DM. Front Cell Dev Biol. 2024; 2024 Mar 20. PMID: 38572485.
Damage sensing through TLR9 Promotes Viral Clearance and Recovery During Influenza Infection.Kim J, Yuan Y, Agaronyan K, Zhao A, Wang VD, Gupta G, Essayas H, Kaminski A, McGovern J, Yu S, Woo S, Lee CJ, Saleh T, Hu B, Sun Y, Ishikawa G, Bain W, Evankovich J, Herzog EL, Cruz CSD, Ryu C, Sharma L. bioRxiv. 2024 Mar 6; 2024 Mar 6. PMID: 38496452.
Adaptive multi-interventional trial platform to improve patient care for fibrotic interstitial lung diseases.Kawano-Dourado L, Kulkarni T, Ryerson CJ, Rivera-Ortega P, Baldi BG, Chaudhuri N, Funke-Chambour M, Hoffmann-Vold AM, Johannson KA, Khor YH, Montesi SB, Piccari L, Prosch H, Molina-Molina M, Sellares Torres J, Bauer-Ventura I, Rajan S, Jacob J, Richards D, Spencer LG, Wendelberger B, Jensen T, Quintana M, Kreuter M, Gordon AC, Martinez FJ, Kaminski N, Cornelius V, Lewis R, Adams W, Jenkins G. Thorax. 2024 Mar 6; 2024 Mar 6. PMID: 38448221.
Challenges and perspectives in computational deconvolution of genomics data.Garmire LX, Li Y, Huang Q, Xu C, Teichmann SA, Kaminski N, Pellegrini M, Nguyen Q, Teschendorff AE. Nat Methods. 2024 Mar; 2024 Feb 19. PMID: 38374264.
Mast-cell expressed membrane protein-1 is expressed in classical monocytes and alveolar macrophages in idiopathic pulmonary fibrosis and regulates cell chemotaxis, adhesion, and migration in a TGFβ-dependent manner.Perrot CY, Karampitsakos T, Unterman A, Adams T, Marlin K, Arsenault A, Zhao A, Kaminski N, Katlaps G, Patel K, Bandyopadhyay D, Herazo-Maya JD. Am J Physiol Cell Physiol. 2024 Mar 1; 2024 Jan 8. PMID: 38189137.
The Emerging Spectrum of Somatic Mutation in Rheumatic Disease: Clonal Hematopoiesis Connects Aging With Giant Cell Arteritis.Bucala R, Tsao BP. Arthritis Rheumatol. 2024 Mar; 2024 Jan 3. PMID: 37961826.
Anti-Inflammatory Roles of Type I Interferon Signaling in the Lung.Feng J, Liu Y, Kim J, Ahangari F, Kaminski N, Bain WG, Jie Z, Dela Cruz CS, Sharma L. Am J Physiol Lung Cell Mol Physiol. 2024 Feb 20; 2024 Feb 20. PMID: 38375579.
Association study of human leukocyte antigen variants and idiopathic pulmonary fibrosis.Guillen-Guio B, Paynton ML, Allen RJ, Chin DPW, Donoghue LJ, Stockwell A, Leavy OC, Hernandez-Beeftink T, Reynolds C, Cullinan P, Martinez F, Booth HL, Fahy WA, Hall IP, Hart SP, Hill MR, Hirani N, Hubbard RB, McAnulty RJ, Millar AB, Navaratnam V, Oballa E, Parfrey H, Saini G, Sayers I, Tobin MD, Whyte MKB, Adegunsoye A, Kaminski N, Ma SF, Strek ME, Zhang Y, Fingerlin TE, Molina-Molina M, Neighbors M, Sheng XR, Oldham JM, Maher TM, Molyneaux PL, Flores C, Noth I, Schwartz DA, Yaspan BL, Jenkins RG, Wain LV, Hollox EJ. ERJ Open Res. 2024 Jan; 2024 Feb 19. PMID: 38375425.
Pulmonary Fibrosis Stakeholder Summit: A Joint NHLBI, Three Lakes Foundation, and Pulmonary Fibrosis Foundation Workshop Report.Montesi SB, Gomez CR, Beers M, Brown R, Chattopadhyay I, Flaherty KR, Garcia CK, Gomperts B, Hariri LP, Hogaboam CM, Jenkins RG, Kaminski N, Kim GHJ, Königshoff M, Kolb M, Kotton DN, Kropski JA, Lasky J, Magin CM, Maher TM, McCormick M, Moore BB, Nickerson-Nutter C, Oldham J, Podolanczuk AJ, Raghu G, Rosas I, Rowe SM, Schmidt WT, Schwartz D, Shore JE, Spino C, Craig JM, Martinez FJ. Am J Respir Crit Care Med. 2024 Feb 15. PMID: 38113442.
Impact of Structured Reporting For Lung Cancer Screening Low-Dose CT Scan Incidental Findings on Physician Management.Kunitomo Y, Sather P, Killam J, Pisani M, Slade MD, Tanoue L. Chest. 2024 Feb 10; 2024 Feb 10. PMID: 38346557.
Fossil Industry and Respiratory Societies: Time for a Clear Stand.Piccari L, Kaminski N, Mann ME. Am J Respir Crit Care Med. 2024 Feb 1. PMID: 37796608.
EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth.Kuhlmann-Hogan A, Cordes T, Xu Z, Kuna RS, Traina KA, Robles-Oteíza C, Ayeni D, Kwong EM, Levy S, Globig AM, Nobari MM, Cheng GZ, Leibel SL, Homer RJ, Shaw RJ, Metallo CM, Politi K, Kaech SM. Cancer Discov. 2024 Jan 25; 2024 Jan 25. PMID: 38270272.
Single-cell transcriptomic analysis of human pleura reveals stromal heterogeneity and informs in vitro models of mesothelioma.Obacz J, Valer JA, Nibhani R, Adams TS, Schupp JC, Veale N, Lewis-Wade A, Flint J, Hogan J, Aresu G, Coonar AS, Peryt A, Biffi G, Kaminski N, Francies H, Rassl DM, Garnett MJ, Rintoul RC, Marciniak SJ. Eur Respir J. 2024 Jan; 2024 Jan 25. PMID: 38212075.
Assessment of Pathology Domain-Specific Knowledge of ChatGPT and Comparison to Human Performance.Wang AY, Lin S, Tran C, Homer RJ, Wilsdon D, Walsh JC, Goebel EA, Sansano I, Sonawane S, Cockenpot V, Mukhopadhyay S, Taskin T, Zahra N, Cima L, Semerci O, Özamrak BG, Mishra P, Vennavalli NS, Chen PC, Cecchini MJ. Arch Pathol Lab Med. 2024 Jan 20; 2024 Jan 20. PMID: 38244054.
Potential role of RhoA GTPase regulation in type interferon signaling in systemic lupus erythematosus.Fan W, Wei B, Chen X, Zhang Y, Xiao P, Li K, Zhang YQ, Huang J, Leng L, Bucala R. Arthritis Res Ther. 2024 Jan 20; 2024 Jan 20. PMID: 38243295.
EGFR-driven lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth.Kuhlmann-Hogan A, Cordes T, Xu Z, Kuna RS, Traina KA, Robles-Oteiza C, Ayeni D, Kwong EM, Levy S, Globig AM, Nobari MM, Cheng GZ, Leibel SL, Homer RJ, Shaw RJ, Metallo CM, Politi K, Kaech SM. Cancer Discov. 2024 Jan 19; 2024 Jan 19. PMID: 38241033.
Genome-wide SNP-sex interaction analysis of susceptibility to idiopathic pulmonary fibrosis.Leavy OC, Goemans AF, Stockwell AD, Allen RJ, Guillen-Guio B, Hernandez-Beeftink T, Adegunsoye A, Booth HL, Cullinan P, Fahy WA, Fingerlin TE, Virk HS, Hall IP, Hart SP, Hill MR, Hirani N, Hubbard RB, Kaminski N, Ma SF, McAnulty RJ, Sheng XR, Millar AB, Molina-Molina M, Navaratnam V, Neighbors M, Parfrey H, Saini G, Sayers I, Strek ME, Tobin MD, Whyte MK, Zhang Y, Maher TM, Molyneaux PL, Oldham JM, Yaspan BL, Flores C, Martinez F, Reynolds CJ, Schwartz DA, Noth I, Jenkins RG, Wain LV. medRxiv. 2024 Jan 15; 2024 Jan 15. PMID: 38293162.
Organ Boundary Circuits Regulate Sox9+ Alveolar Tuft Cells During Post-Pneumonectomy Lung Regeneration.Obata T, Mizoguchi S, Greaney AM, Adams T, Yuan Y, Edelstein S, Leiby KL, Rivero R, Wang N, Kim H, Yang J, Schupp JC, Stitelman D, Tsuchiya T, Levchenko A, Kaminski N, Niklason LE, Brickman Raredon MS. bioRxiv. 2024 Jan 8; 2024 Jan 8. PMID: 38260691.
MIF contribution to progressive brain diseases.Matejuk A, Benedek G, Bucala R, Matejuk S, Offner H, Vandenbark AA. J Neuroinflammation. 2024 Jan 4; 2024 Jan 4. PMID: 38178143.
Increased expression of CXCL6 in secretory cells drives fibroblast collagen synthesis and is associated with increased mortality in idiopathic pulmonary fibrosis.Bahudhanapati H, Tan J, Apel RM, Seeliger B, Schupp J, Li X, Sullivan DI, Sembrat J, Rojas M, Tabib T, Valenzi E, Lafyatis R, Mitash N, Hernandez Pineda R, Jawale C, Peroumal D, Biswas P, Tedrow J, Adams T, Kaminski N, Wuyts WA, McDyer JF, Gibson KF, Alder JK, Königshoff M, Zhang Y, Nouraie M, Prasse A, Kass DJ. Eur Respir J. 2024 Jan; 2024 Jan 4. PMID: 37918852.
Extracellular macrophage migration inhibitory factor (MIF) downregulates adipose hormone-sensitive lipase (HSL) and contributes to obesity.Chen L, Li L, Cui D, Huang Y, Tong H, Zabihi H, Wang S, Qi Y, Lakowski T, Leng L, Liu S, Wu H, Young LH, Bucala R, Qi D. Mol Metab. 2024 Jan; 2023 Nov 5. PMID: 37935315.
Immunology for the Rheumatologist: Arthritis & Rheumatology Introduces a New Problem-Based Immunology Review Series With Great Educational Potential.Bucala R, Solomon DH. Arthritis Rheumatol. 2024 Jan; 2023 Oct 23. PMID: 37655656.

2023

Unagi: Deep Generative Model for Deciphering Cellular Dynamics and In-Silico Drug Discovery in Complex Diseases.Zheng Y, Schupp JC, Adams T, Clair G, Justet A, Ahangari F, Yan X, Hansen P, Carlon M, Cortesi E, Vermant M, Vos R, De Sadeleer LJ, Rosas IO, Pineda R, Sembrat J, Königshoff M, McDonough JE, Vanaudenaerde BM, Wuyts WA, Kaminski N, Ding J. Res Sq. 2023 Dec 18; 2023 Dec 18. PMID: 38196613.
TLR9 ligand sequestration by chemokine CXCL4 negatively affects central B cell tolerance.Çakan E, Ah Kioon MD, Garcia-Carmona Y, Glauzy S, Oliver D, Yamakawa N, Vega Loza A, Du Y, Schickel JN, Boeckers JM, Yang C, Baldo A, Ivashkiv LB, Young RM, Staudt LM, Moody KL, Nündel K, Marshak-Rothstein A, van der Made CI, Hoischen A, Hayward A, Rossato M, Radstake TRDJ, Cunningham-Rundles C, Ryu C, Herzog EL, Barrat FJ, Meffre E. J Exp Med. 2023 Dec 4; 2023 Sep 29. PMID: 37773045.
Aging gene signature of memory CD8(+) T cells is associated with neurocognitive functioning in Alzheimer's disease.Young JJ, Park HJ, Kim M, Par-Young J, Bartlett H, Kim HS, Unlu S, Osmani L, Shin MS, Bucala R, van Dyck CH, Allore H, Mecca AP, You S, Kang I. Immun Ageing. 2023 Dec 2; 2023 Dec 2. PMID: 38042785.
Examination of eQTL Polymorphisms Associated with Increased Risk of Progressive Complicated Sarcoidosis in European and African Descent Subjects.Casanova NG, Camp SM, Gonzalez-Garay ML, Batai K, Garman L, Montgomery CG, Ellis N, Kittles R, Bime C, Hsu AP, Holland S, Lussier YA, Karnes J, Sweiss N, Maier LA, Koth L, Moller DR, Kaminski N, Garcia JGN. Eur J Respir Med. 2023 Dec. PMID: 38390497.
Mitochondrial DNA Sensing Pathogen Recognition Receptors in Systemic Sclerosis Associated Interstitial Lung Disease: A Review.Ghincea A, Woo S, Yu S, Pivarnik T, Fiorini V, Herzog EL, Ryu C. Curr Treatm Opt Rheumatol. 2023 Dec; 2023 Aug 8. PMID: 38230363.
Natural isoaspartyl protein modification of ZAP70 alters T cell responses in lupus.Yang ML, Lam TT, Kanyo J, Kang I, Zhou ZS, Clarke SG, Mamula MJ. Autoimmunity. 2023 Dec; 2023 Nov 23. PMID: 37994408.
Somatic Mutations: The Next Frontier in Demystifying Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis?Yan X, Kaminski N. Am J Respir Crit Care Med. 2023 Dec 1. PMID: 37856835.
Circulating Mitochondrial DNA Is Associated With High Levels of Fatigue in Two Independent Sarcoidosis Cohorts.Fiorini V, Hu B, Sun Y, Yu S, McGovern J, Gandhi S, Woo S, Turcotte-Foster SJ, Pivarnik T, Khan Z, Adams T, Herzog EL, Kaminski N, Gulati M, Ryu C. Chest. 2023 Nov 15; 2023 Nov 15. PMID: 37977267.
Distinguishing features of long COVID identified through immune profiling.Klein J, Wood J, Jaycox JR, Dhodapkar RM, Lu P, Gehlhausen JR, Tabachnikova A, Greene K, Tabacof L, Malik AA, Silva Monteiro V, Silva J, Kamath K, Zhang M, Dhal A, Ott IM, Valle G, Peña-Hernández M, Mao T, Bhattacharjee B, Takahashi T, Lucas C, Song E, McCarthy D, Breyman E, Tosto-Mancuso J, Dai Y, Perotti E, Akduman K, Tzeng TJ, Xu L, Geraghty AC, Monje M, Yildirim I, Shon J, Medzhitov R, Lutchmansingh D, Possick JD, Kaminski N, Omer SB, Krumholz HM, Guan L, Dela Cruz CS, van Dijk D, Ring AM, Putrino D, Iwasaki A. Nature. 2023 Nov; 2023 Sep 25. PMID: 37748514.
Correction: iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjects.Liu Y, Zhao J, Adams TS, Wang N, Schupp JC, Wu W, McDonough JE, Chupp GL, Kaminski N, Wang Z, Yan X. BMC Bioinformatics. 2023 Oct 19; 2023 Oct 19. PMID: 37858060.
Mucosal immune alterations at the early onset of tissue destruction in chronic obstructive pulmonary disease.de Fays C, Geudens V, Gyselinck I, Kerckhof P, Vermaut A, Goos T, Vermant M, Beeckmans H, Kaes J, Van Slambrouck J, Mohamady Y, Willems L, Aversa L, Cortesi EE, Hooft C, Aerts G, Aelbrecht C, Everaerts S, McDonough JE, De Sadeleer LJ, Gohy S, Ambroise J, Janssens W, Ceulemans LJ, Van Raemdonck D, Vos R, Hackett TL, Hogg JC, Kaminski N, Gayan-Ramirez G, Pilette C, Vanaudenaerde BM. Front Immunol. 2023; 2023 Oct 17. PMID: 37915582.
Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation.Pekayvaz K, Gold C, Hoseinpour P, Engel A, Martinez-Navarro A, Eivers L, Coletti R, Joppich M, Dionísio F, Kaiser R, Tomas L, Janjic A, Knott M, Mehari F, Polewka V, Kirschner M, Boda A, Nicolai L, Schulz H, Titova A, Kilani B, Lorenz M, Fingerle-Rowson G, Bucala R, Enard W, Zimmer R, Weber C, Libby P, Schulz C, Massberg S, Stark K. Immunity. 2023 Oct 10; 2023 Aug 30. PMID: 37652021.
Cardiothoracic complications of immune checkpoint inhibitors.Gosangi B, Wang Y, Rubinowitz AN, Kwan J, Traube L, Gange C, Bader AS. Clin Imaging. 2023 Oct; 2023 Aug 9. PMID: 37659356.
Alveolar Vascular Remodeling in Nonspecific Interstitial Pneumonia: Replacement of Normal Lung Capillaries with COL15A1-Positive Endothelial Cells.Schupp JC, Manning EP, Chioccioli M, Kamp JC, Christian L, Ryu C, Herzog E, Kühnel MP, Prasse A, Kaminski N, Jonigk DD, Homer RJ. Am J Respir Crit Care Med. 2023 Oct 1. PMID: 37552025.
Genetic analyses of chr11p15.5 region identify MUC5AC-MUC5B associated with asthma-related phenotypes.Li X, Li H, Christenson SA, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston BM, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Zein J, Kaminski N, Wenzel SE, Woodruff PG, Bleecker ER, Meyers DA. J Asthma. 2023 Oct; 2023 Apr 21. PMID: 36946148.
SRC and TKS5 mediated podosome formation in fibroblasts promotes extracellular matrix invasion and pulmonary fibrosis.Barbayianni I, Kanellopoulou P, Fanidis D, Nastos D, Ntouskou ED, Galaris A, Harokopos V, Hatzis P, Tsitoura E, Homer R, Kaminski N, Antoniou KM, Crestani B, Tzouvelekis A, Aidinis V. Nat Commun. 2023 Sep 21; 2023 Sep 21. PMID: 37735172.
The RhoA GTPase regulates Type I Interferon Signaling in Systemic lupus erythematosus.Fan W, Wei B, Chen X, Zhang Y, Xiao P, Li K, Zhang YQ, Huang J, Leng L, Bucala R. Res Sq. 2023 Sep 20; 2023 Sep 20. PMID: 37790522.
When Development of the Alveolar Gas Exchange Unit Fails: Universal Single-Cell Lessons from Rare Monogenic Disorders.Schupp JC, Kaminski N. Am J Respir Crit Care Med. 2023 Sep 15. PMID: 37555730.
An AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model.Charkoftaki G, Aalizadeh R, Santos-Neto A, Tan WY, Davidson EA, Nikolopoulou V, Wang Y, Thompson B, Furnary T, Chen Y, Wunder EA, Coppi A, Schulz W, Iwasaki A, Pierce RW, Cruz CSD, Desir GV, Kaminski N, Farhadian S, Veselkov K, Datta R, Campbell M, Thomaidis NS, Ko AI, Thompson DC, Vasiliou V. Hum Genomics. 2023 Aug 29; 2023 Aug 29. PMID: 37641126.
iDESC: identifying differential expression in single-cell RNA sequencing data with multiple subjects.Liu Y, Zhao J, Adams TS, Wang N, Schupp JC, Wu W, McDonough JE, Chupp GL, Kaminski N, Wang Z, Yan X. BMC Bioinformatics. 2023 Aug 22; 2023 Aug 22. PMID: 37608264.
Polymer nanoparticles deliver mRNA to the lung for mucosal vaccination.Suberi A, Grun MK, Mao T, Israelow B, Reschke M, Grundler J, Akhtar L, Lee T, Shin K, Piotrowski-Daspit AS, Homer RJ, Iwasaki A, Suh HW, Saltzman WM. Sci Transl Med. 2023 Aug 16; 2023 Aug 16. PMID: 37585505.
Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer.de Miguel FJ, Gentile C, Feng WW, Silva SJ, Sankar A, Exposito F, Cai WL, Melnick MA, Robles-Oteiza C, Hinkley MM, Tsai JA, Hartley AV, Wei J, Wurtz A, Li F, Toki MI, Rimm DL, Homer R, Wilen CB, Xiao AZ, Qi J, Yan Q, Nguyen DX, Jänne PA, Kadoch C, Politi KA. Cancer Cell. 2023 Aug 14; 2023 Aug 3. PMID: 37541244.
Integrative genetic and genomic networks identify microRNA associated with COPD and ILD.Pavel AB, Garrison C, Luo L, Liu G, Taub D, Xiao J, Juan-Guardela B, Tedrow J, Alekseyev YO, Yang IV, Geraci MW, Sciurba F, Schwartz DA, Kaminski N, Beane J, Spira A, Lenburg ME, Campbell JD. Sci Rep. 2023 Aug 11; 2023 Aug 11. PMID: 37567908.
Integrative analyses for the identification of idiopathic pulmonary fibrosis-associated genes and shared loci with other diseases.Chen M, Zhang Y, Adams T, Ji D, Jiang W, Wain LV, Cho M, Kaminski N, Zhao H. Thorax. 2023 Aug; 2022 Oct 10. PMID: 36216496.
A statistical framework to identify cell types whose genetically regulated proportions are associated with complex diseases.Liu W, Deng W, Chen M, Dong Z, Zhu B, Yu Z, Tang D, Sauler M, Lin C, Wain LV, Cho MH, Kaminski N, Zhao H. PLoS Genet. 2023 Jul; 2023 Jul 31. PMID: 37523391.
Association study of human leukocyte antigen (HLA) variants and idiopathic pulmonary fibrosis.Guillen-Guio B, Paynton ML, Allen RJ, Chin DPW, Donoghue LJ, Stockwell A, Leavy OC, Hernandez-Beeftink T, Reynolds C, Cullinan P, Martinez F, Booth HL, Fahy WA, Hall IP, Hart SP, Hill MR, Hirani N, Hubbard RB, McAnulty RJ, Millar AB, Navaratnam V, Oballa E, Parfrey H, Saini G, Sayers I, Tobin MD, Whyte MKB, Adegunsoye A, Kaminski N, Shwu-Fan M, Strek ME, Zhang Y, Fingerlin TE, Molina-Molina M, Neighbors M, Sheng XR, Oldham JM, Maher TM, Molyneaux PL, Flores C, Noth I, Schwartz DA, Yaspan BL, Jenkins RG, Wain LV, Hollox EJ. medRxiv. 2023 Jul 24; 2023 Jul 24. PMID: 37546732.
COVID-19 annual update: a narrative review.Biancolella M, Colona VL, Luzzatto L, Watt JL, Mattiuz G, Conticello SG, Kaminski N, Mehrian-Shai R, Ko AI, Gonsalves GS, Vasiliou V, Novelli G, Reichardt JKV. Hum Genomics. 2023 Jul 24; 2023 Jul 24. PMID: 37488607.
Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are significant promotors of UVB- but not chemically induced non-melanoma skin cancer.Huth S, Huth L, Heise R, Marquardt Y, Lopopolo L, Piecychna M, Boor P, Fingerle-Rowson G, Kapurniotu A, Yazdi AS, Bucala R, Bernhagen J, Baron JM. Sci Rep. 2023 Jul 18; 2023 Jul 18. PMID: 37464010.
The MIF promoter SNP rs755622 is associated with immune activation in glioblastoma.Alban TJ, Grabowski MM, Otvos B, Bayik D, Wang W, Zalavadia A, Makarov V, Troike K, McGraw M, Rabljenovic A, Lauko A, Neumann C, Roversi G, Waite KA, Cioffi G, Patil N, Tran TT, McCortney K, Steffens A, Diaz CM, Brown JM, Egan KM, Horbinski CM, Barnholtz-Sloan JS, Rajappa P, Vogelbaum MA, Bucala R, Chan TA, Ahluwalia MS, Lathia JD. JCI Insight. 2023 Jul 10; 2023 Jul 10. PMID: 37252795.
VISTA (PD-1H) Is a Crucial Immune Regulator to Limit Pulmonary Fibrosis.Kim SH, Adams TS, Hu Q, Shin HJ, Chae G, Lee SE, Sharma L, Kwon HK, Lee FY, Park HJ, Huh WJ, Manning E, Kaminski N, Sauler M, Chen L, Song JW, Kim TK, Kang MJ. Am J Respir Cell Mol Biol. 2023 Jul. PMID: 36450109.
A pref-1-controlled non-inflammatory mechanism of insulin resistance.Huang Y, Cui D, Chen L, Tong H, Wu H, Muller GK, Qi Y, Wang S, Xu J, Gao X, Fifield KE, Wang L, Xia Z, Vanderluit JL, Liu S, Leng L, Sun G, McGuire J, Young LH, Bucala R, Qi D. iScience. 2023 Jun 16; 2023 May 19. PMID: 37283810.
A Picture Worth a Thousand Words, Created with One Sentence: Using Artificial Intelligence-created Art to Enhance Medical Education.Huston JC, Kaminski N. ATS Sch. 2023 Jun; 2023 May 10. PMID: 37533539.
An integrated cell atlas of the lung in health and disease.Sikkema L, Ramírez-Suástegui C, Strobl DC, Gillett TE, Zappia L, Madissoon E, Markov NS, Zaragosi LE, Ji Y, Ansari M, Arguel MJ, Apperloo L, Banchero M, Bécavin C, Berg M, Chichelnitskiy E, Chung MI, Collin A, Gay ACA, Gote-Schniering J, Hooshiar Kashani B, Inecik K, Jain M, Kapellos TS, Kole TM, Leroy S, Mayr CH, Oliver AJ, von Papen M, Peter L, Taylor CJ, Walzthoeni T, Xu C, Bui LT, De Donno C, Dony L, Faiz A, Guo M, Gutierrez AJ, Heumos L, Huang N, Ibarra IL, Jackson ND, Kadur Lakshminarasimha Murthy P, Lotfollahi M, Tabib T, Talavera-López C, Travaglini KJ, Wilbrey-Clark A, Worlock KB, Yoshida M, van den Berge M, Bossé Y, Desai TJ, Eickelberg O, Kaminski N, Krasnow MA, Lafyatis R, Nikolic MZ, Powell JE, Rajagopal J, Rojas M, Rozenblatt-Rosen O, Seibold MA, Sheppard D, Shepherd DP, Sin DD, Timens W, Tsankov AM, Whitsett J, Xu Y, Banovich NE, Barbry P, Duong TE, Falk CS, Meyer KB, Kropski JA, Pe'er D, Schiller HB, Tata PR, Schultze JL, Teichmann SA, Misharin AV, Nawijn MC, Luecken MD, Theis FJ. Nat Med. 2023 Jun; 2023 Jun 8. PMID: 37291214.
Vascular-Parenchymal Cross-Talk Promotes Lung Fibrosis through BMPR2 Signaling.Yanagihara T, Tsubouchi K, Zhou Q, Chong M, Otsubo K, Isshiki T, Schupp JC, Sato S, Scallan C, Upagupta C, Revill S, Ayoub A, Chong SG, Dvorkin-Gheva A, Kaminski N, Tikkanen J, Keshavjee S, Paré G, Guignabert C, Ask K, Kolb MRJ. Am J Respir Crit Care Med. 2023 Jun 1. PMID: 36917778.
Medical Societies Must Choose Professional Meeting Locations Responsibly in a Post-Roe World.Lee AG, Maley J, Hibbert K, Akgün KM, Hauschildt KE, Law A, Kaminski N, Hayes M, Gesthalter Y, Bosslet GT, Santhosh L, Witkin A, Hills-Dunlap K, Çoruh B, Gershengorn HB, Hardin CC. Ann Am Thorac Soc. 2023 Jun. PMID: 36812378.
PCSK6 and Survival in Idiopathic Pulmonary Fibrosis.Oldham JM, Allen RJ, Lorenzo-Salazar JM, Molyneaux PL, Ma SF, Joseph C, Kim JS, Guillen-Guio B, Hernández-Beeftink T, Kropski JA, Huang Y, Lee CT, Adegunsoye A, Pugashetti JV, Linderholm AL, Vo V, Strek ME, Jou J, Muñoz-Barrera A, Rubio-Rodriguez LA, Hubbard R, Hirani N, Whyte MKB, Hart S, Nicholson AG, Lancaster L, Parfrey H, Rassl D, Wallace W, Valenzi E, Zhang Y, Mychaleckyj J, Stockwell A, Kaminski N, Wolters PJ, Molina-Molina M, Banovich NE, Fahy WA, Martinez FJ, Hall IP, Tobin MD, Maher TM, Blackwell TS, Yaspan BL, Jenkins RG, Flores C, Wain LV, Noth I. Am J Respir Crit Care Med. 2023 Jun 1. PMID: 36780644.
Emergence of division of labor in tissues through cell interactions and spatial cues.Adler M, Moriel N, Goeva A, Avraham-Davidi I, Mages S, Adams TS, Kaminski N, Macosko EZ, Regev A, Medzhitov R, Nitzan M. Cell Rep. 2023 May 30; 2023 Apr 21. PMID: 37086403.
Urothelial Oxidative Stress and ERK Activation Mediate HMGB1-Induced Bladder Pain.Ye S, Mahmood DFD, Ma F, Leng L, Bucala R, Vera PL. Cells. 2023 May 22; 2023 May 22. PMID: 37408274.
Correction: Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3.Lee CM, He CH, Park JW, Lee JH, Kamle S, Ma B, Akosman B, Cotez R, Chen E, Zhou Y, Herzog EL, Ryu C, Peng X, Rosas IO, Poli S, Bostwick CF, Choi AM, Elias JA, Lee CG. Life Sci Alliance. 2023 May; 2023 Apr 10. PMID: 37037591.
α1 Adrenoreceptor antagonism mitigates extracellular mitochondrial DNA accumulation in lung fibrosis models and in patients with idiopathic pulmonary fibrosis.Ishikawa G, Peng X, McGovern J, Woo S, Perry C, Liu A, Yu S, Ghincea A, Kishchanka A, Fiorini V, Hu B, Sun Y, Sun H, Ryu C, Herzog EL. Am J Physiol Lung Cell Mol Physiol. 2023 May 1; 2023 Jan 17. PMID: 36648147.
Single-cell profiling reveals immune aberrations in progressive idiopathic pulmonary fibrosis.Unterman A, Zhao AY, Neumark N, Schupp JC, Ahangari F, Cosme C Jr, Sharma P, Flint J, Stein Y, Ryu C, Ishikawa G, Sumida TS, Gomez JL, Herazo-Maya J, Dela Cruz CS, Herzog EL, Kaminski N. medRxiv. 2023 Apr 29; 2023 Apr 29. PMID: 37163015.
Rational engineering of lung alveolar epithelium.Leiby KL, Yuan Y, Ng R, Raredon MSB, Adams TS, Baevova P, Greaney AM, Hirschi KK, Campbell SG, Kaminski N, Herzog EL, Niklason LE. NPJ Regen Med. 2023 Apr 28; 2023 Apr 28. PMID: 37117221.
Thyroid hormone modulates hyperoxic neonatal lung injury and mitochondrial function.Vamesu BM, Nicola T, Li R, Hazra S, Matalon S, Kaminski N, Ambalavanan N, Kandasamy J. JCI Insight. 2023 Apr 24; 2023 Apr 24. PMID: 36917181.
A Multi-omic Analysis of the Human Lung Reveals Distinct Cell Specific Aging and Senescence Molecular Programs.De Man R, McDonough JE, Adams TS, Manning EP, Myers G, Vos R, Ceulemans L, Dupont L, Vanaudenaerde BM, Wuyts WA, Rosas IO, Hagood JS, Ambalavanan N, Niklason L, Hansen KC, Yan X, Kaminski N. bioRxiv. 2023 Apr 19; 2023 Apr 19. PMID: 37131739.
ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant Lung Cancer in Permissive Cellular Contexts.Hu B, Wiesehöfer M, de Miguel FJ, Liu Z, Chan LH, Choi J, Melnick MA, Arnal Estape A, Walther Z, Zhao D, Lopez-Giraldez F, Wurtz A, Cai G, Fan R, Gettinger S, Xiao A, Yan Q, Homer R, Nguyen DX, Politi K. Cancer Res. 2023 Apr 15. PMID: 38359163.
Autoimmune comorbidities associated with sarcoidosis: a case-control study in the All of Us research program.Murphy MJ, Edemobi P, Leasure AC, Gulati M, Miller EJ, Damsky W, Cohen JM. Rheumatol Adv Pract. 2023; 2023 Apr 12. PMID: 38606002.
Aging gene signature of IL-7 receptor alpha low effector memory CD8(+) T cells is associated with neurocognitive functioning in Alzheimer's disease.Young J, Park HJ, Kim M, Par-Young J, Bartlett H, Kim HS, Unlu S, Osmani L, Shin MS, Bucala R, van Dyck C, Allore H, Mecca A, You S, Kang I. Res Sq. 2023 Apr 4; 2023 Apr 4. PMID: 37066364.
Proteomic profiling demonstrates inflammatory and endotheliopathy signatures associated with impaired cardiopulmonary exercise hemodynamic profile in Post Acute Sequelae of SARS-CoV-2 infection (PASC) syndrome.Singh I, Leitner BP, Wang Y, Zhang H, Joseph P, Lutchmansingh DD, Gulati M, Possick JD, Damsky W, Hwa J, Heerdt PM, Chun HJ. Pulm Circ. 2023 Apr; 2023 Apr 1. PMID: 37091121.
Transbronchial Lung Cryobiopsy for the Diagnosis of Interstitial Lung Disease: A Right Answer to a Wrong Question Is Still a Wrong Answer.Low SW, Kaminski N, Maldonado F. J Bronchology Interv Pulmonol. 2023 Apr 1; 2023 Apr 1. PMID: 37005378.
SH2 Domain-Containing Phosphatase-SHP2 Attenuates Fibrotic Responses through Negative Regulation of Mitochondrial Metabolism in Lung Fibroblasts.Karampitsakos T, Galaris A, Barbayianni I, DeIuliis G, Ahangari F, Sampsonas F, Sotiropoulou V, Aidinis V, Bennett AM, Herazo-Maya JD, Xylourgidis N, Bakakos P, Bouros D, Kaminski N, Tzouvelekis A. Diagnostics (Basel). 2023 Mar 18; 2023 Mar 18. PMID: 36980473.
Lung cancer with air lucency: a systematic review and clinical management guide.Detterbeck FC, Kumbasar U, Li AX, Rubinowitz AN, Traube L, Gosangi B, Udelsman BV, Bade BC, Ely S, Barreto G, Tanoue LT, Marom EM, Rivera MP. J Thorac Dis. 2023 Feb 28; 2023 Feb 23. PMID: 36910113.
microRNA-33 deficiency in macrophages enhances autophagy, improves mitochondrial homeostasis, and protects against lung fibrosis.Ahangari F, Price NL, Malik S, Chioccioli M, Bärnthaler T, Adams TS, Kim J, Pradeep SP, Ding S, Cosmos C Jr, Rose KS, McDonough JE, Aurelien NR, Ibarra G, Omote N, Schupp JC, DeIuliis G, Villalba Nunez JA, Sharma L, Ryu C, Dela Cruz CS, Liu X, Prasse A, Rosas I, Bahal R, Fernández-Hernando C, Kaminski N. JCI Insight. 2023 Feb 22; 2023 Feb 22. PMID: 36626225.
Low CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma Severity.Li X, Guerra S, Ledford JG, Kraft M, Li H, Hastie AT, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Zein J, Kaminski N, Wenzel SE, Woodruff PG, Meyers DA, Bleecker ER. Am J Respir Crit Care Med. 2023 Feb 15. PMID: 36066606.
Lung Cell Atlases in Health and Disease.Adams TS, Marlier A, Kaminski N. Annu Rev Physiol. 2023 Feb 10; 2022 Nov 9. PMID: 36351366.
Single-cell RNA-seq uncovers cellular heterogeneity and provides a signature for paediatric sleep apnoea.Cortese R, Adams TS, Cataldo KH, Hummel J, Kaminski N, Kheirandish-Gozal L, Gozal D. Eur Respir J. 2023 Feb; 2023 Feb 9. PMID: 36356973.
"Long Haulers".Lutchmansingh DD, Higuero Sevilla JP, Possick JD, Gulati M. Semin Respir Crit Care Med. 2023 Feb; 2023 Jan 16. PMID: 36646091.
Correction to: Clinical features and high-risk indicators of central nervous system involvement in primary Sjögren's syndrome.Fan W, Par-Young J, Li K, Zhang Y, Xiao P, Hua L, Leng L, Chen X, Bucala R. Clin Rheumatol. 2023 Feb. PMID: 36565380.
Clinical features and high-risk indicators of central nervous system involvement in primary Sjögren's syndrome.Fan W, Par-Young J, Li K, Zhang Y, Xiao P, Hua L, Leng L, Chen X, Bucala R. Clin Rheumatol. 2023 Feb; 2022 Nov 19. PMID: 36401063.
PD-1(high)CXCR5(-)CD4(+) peripheral helper T cells promote CXCR3(+) plasmablasts in human acute viral infection.Asashima H, Mohanty S, Comi M, Ruff WE, Hoehn KB, Wong P, Klein J, Lucas C, Cohen I, Coffey S, Lele N, Greta L, Raddassi K, Chaudhary O, Unterman A, Emu B, Kleinstein SH, Montgomery RR, Iwasaki A, Dela Cruz CS, Kaminski N, Shaw AC, Hafler DA, Sumida TS. Cell Rep. 2023 Jan 31; 2023 Jan 2. PMID: 36596303.
A novel Bayesian framework for harmonizing information across tissues and studies to increase cell type deconvolution accuracy.Deng W, Li B, Wang J, Jiang W, Yan X, Li N, Vukmirovic M, Kaminski N, Wang J, Zhao H. Brief Bioinform. 2023 Jan 19. PMID: 36631398.
Changes in microRNAs during Storage and Processing of Breast Milk.Kim JH, Kim KU, Min H, Lee ES, Lim IS, Song J, Kang I, Yi DY. Metabolites. 2023 Jan 17; 2023 Jan 17. PMID: 36837760.
Reflections for the 50th Anniversary of The Journal of Rheumatology: The Past, Present, and Future of Rheumatology.Masi AT, Bucala RJ. J Rheumatol. 2023 Jan. PMID: 36587952.
Comprehensive visualization of cell-cell interactions in single-cell and spatial transcriptomics with NICHES.Raredon MSB, Yang J, Kothapalli N, Lewis W, Kaminski N, Niklason LE, Kluger Y. Bioinformatics. 2023 Jan 1. PMID: 36458905.
Effect of Androgen-Androgen Receptor Directed Therapy on COVID-19 Outcome in Prostate Cancer Patients.Ünlü S, Shin JJ, Par-Young J, Simonov M, Vinetz J, Petrylak DP, Kang I, Kim JW. Cancer Invest. 2023 Jan; 2022 Nov 17. PMID: 36373994.
IFN-γ Is Protective in Cytokine Release Syndrome-associated Extrapulmonary Acute Lung Injury.Sun Y, Hu B, Stanley G, Harris ZM, Gautam S, Homer R, Koff JL, Rajagopalan G. Am J Respir Cell Mol Biol. 2023 Jan. PMID: 36125351.
Longitudinal lung function and gas transfer in individuals with idiopathic pulmonary fibrosis: a genome-wide association study.Allen RJ, Oldham JM, Jenkins DA, Leavy OC, Guillen-Guio B, Melbourne CA, Ma SF, Jou J, Kim JS, Fahy WA, Oballa E, Hubbard RB, Navaratnam V, Braybrooke R, Saini G, Roach KM, Tobin MD, Hirani N, Whyte MKB, Kaminski N, Zhang Y, Martinez FJ, Linderholm AL, Adegunsoye A, Strek ME, Maher TM, Molyneaux PL, Flores C, Noth I, Gisli Jenkins R, Wain LV. Lancet Respir Med. 2023 Jan; 2022 Aug 16. PMID: 35985358.

2022

Implication of IL-7 receptor alpha chain expression by CD8(+) T cells and its signature in defining biomarkers in aging.Shin MS, Park HJ, Young J, Kang I. Immun Ageing. 2022 Dec 21; 2022 Dec 21. PMID: 36544153.
Metagenomic sequencing of the bronchoalveolar lavage extracellular virome and cellular transcriptome of sarcoidosis patients does not detect rubella virus.Keeler EL, Vukmirovic M, Yan X, Gulino K, Ghedin E, Kaminski N, Sullivan KE, Bushman FD, Collman RG, Rosenbach M. Sarcoidosis Vasc Diffuse Lung Dis. 2022 Dec 19; 2022 Dec 19. PMID: 36533601.
Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis.Ahangari F, Becker C, Foster DG, Chioccioli M, Nelson M, Beke K, Wang X, Justet A, Adams T, Readhead B, Meador C, Correll K, Lili LN, Roybal HM, Rose KA, Ding S, Barnthaler T, Briones N, DeIuliis G, Schupp JC, Li Q, Omote N, Aschner Y, Sharma L, Kopf KW, Magnusson B, Hicks R, Backmark A, Dela Cruz CS, Rosas I, Cousens LP, Dudley JT, Kaminski N, Downey GP. Am J Respir Crit Care Med. 2022 Dec 15. PMID: 35998281.
Imaging in the Intensive Care Unit.Toy D, Siegel MD, Rubinowitz AN. Semin Respir Crit Care Med. 2022 Dec; 2022 Nov 28. PMID: 36442475.
Macrophage migration inhibitory factor regulates specific innate immune sensor responses in gingival epithelial cells.Kantrong N, Chang AM, Bamashmous S, Hajjar AM, Bucala RJ, Darveau RP. J Periodontol. 2022 Dec; 2022 Feb 24. PMID: 35100435.
Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses.Mao T, Israelow B, Peña-Hernández MA, Suberi A, Zhou L, Luyten S, Reschke M, Dong H, Homer RJ, Saltzman WM, Iwasaki A. Science. 2022 Nov 25; 2022 Nov 25. PMID: 36302057.
Ameliorating Fibrosis in Murine and Human Tissues with END55, an Endostatin-Derived Fusion Protein Made in Plants.Mlakar L, Garrett SM, Watanabe T, Sanderson M, Nishimoto T, Heywood J, Helke KL, Pilewski JM, Herzog EL, Feghali-Bostwick C. Biomedicines. 2022 Nov 9; 2022 Nov 9. PMID: 36359382.
CD74 as a regulator of transcription in normal B cells.David K, Friedlander G, Pellegrino B, Radomir L, Lewinsky H, Leng L, Bucala R, Becker-Herman S, Shachar I. Cell Rep. 2022 Nov 1. PMID: 36323260.