Yale Adult Cystic Fibrosis

The Yale University Adult Cystic Fibrosis Center, accredited by the national Cystic Fibrosis Foundation, specializes in the diagnosis, management, treatment and research of cystic fibrosis. We provide a team approach to care that includes medical, nurse, registered dietician, physical therapy, social worker, and respiratory therapy cystic fibrosis specialists. We collaborate closely with our colleagues in the Yale University Pediatric Cystic Fibrosis Center to assist adolescents and young adults in the transition from pediatric to adult care.

Our mission

  1. To provide effective, evidence-based care for adults with cystic fibrosis.
  2. To investigate and to implement new treatments for cystic fibrosis.
  3. To advance the scientific understanding of cystic fibrosis.
  4. To train providers of adult cystic fibrosis care.

Our services

  • Comprehensive cystic fibrosis diagnosis including sweat testing and blood testing for all known mutations related to cystic fibrosis.
  • Full range of treatments for all complications related to cystic fibrosis, including those involving the respiratory, sinus, digestive, endocrine, and reproductive systems.
  • Management of cystic fibrosis lung disease, including mucus clearance techniques, mucolytics, and preventive therapy for patients infected with pseudomonas.
  • Comprehensive nutrition counseling and care, including pancreatic enzyme replacement therapy, screening for and repletion of vitamin deficiencies.
  • Cystic fibrosis education and counseling.

Latest News

Our Physicians

Koff, Jonathan

Director, Yale Adult Cystic Fibrosis

Assistant Professor of Medicine (Pulmonary)
Director, Adult Cystic Fibrosis Program

Research Interests:Airway epithelial inflammation; Innate immunity; Mucosal immunology; EGFR signaling

Clinical Interests:Bronchiectasis; diagnosis and care of cystic fibrosis.

Britto-Leon, Clemente Jose

Instructor in Medicine (Pulmonary)

Research Interests:Airway epithelium; airway inflammation; innate immunity; SPLUNC1; BPIFA1

Clinical Interests:Cystic fibrosis; asthma; airway diseases

Talwalkar, Jaideep

Assistant Professor of Medicine (General Medicine)
Associate Director, Yale Cystic Fibrosis Adult Program
Assistant Professor of Pediatrics
Associate Director, Yale Combined Med-Peds Residency Program
Director of Clinical Skills, Yale School of Medicine
Faculty Advisor, Yale Resident Spanish-language Initiative

Research Interests:Medical education; Curriculum development and evaluation; Cystic fibrosis; Transition of care

Clinical Interests:primary care pediatrics; primary care internal medicine; cystic fibrosis; transition of care