Roy S. Herbst MD, PhD

Ensign Professor of Medicine (Medical Oncology) and Professor of Pharmacology; Chief of Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven; Associate Director for Translational Research, Yale Cancer Center; Clinical Research Program Leader, Thoracic Oncology Program, Yale Cancer Center

Departments & Organizations

Cancer Center, Yale: Thoracic Oncology Program | Developmental Therapeutics


Medical Oncology

Research Interests

Early phase clinical trials; Biomarker studies; Personalized medicine for cancer treatment. more...


  • B.S., Yale University, 1984
  • M.S., Yale University, 1984
  • Ph.D., Rockefeller University, 1990
  • M.D., Cornell University Medical College, 1991
  • MMS, Harvard University, 1997

Selected Publications

  • Multitargeted tyrosine kinase inhibitors in unselected patients with advanced non-small-cell lung cancer (NSCLC): impressions from MONET (the motesanib NSCLC efficacy and tolerability study). Morgensztern D, Herbst RS. J Clin Oncol. 2012 Aug 10;30(23):2805-8.
  • Targeting vascular endothelial growth factor in patients with squamous cell lung cancer. Koo PJ, Morgensztern D, Boyer JL, Herbst RS. J Clin Oncol. 2012 Apr 1;30(10):1137-9.
  • EGFR expression and the flexibility of FLEX. Hirsch FR, Herbst RS. Lancet Oncol. 2012 Jan;13(1):3-5.



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