Yasuko Iwakiri, PhD

Associate Professor of Medicine (Digestive Diseases)

Research Interests

Hypertension, Portal; Liver Cirrhosis; Liver Cirrhosis, Biliary; Vascular Diseases

Public Health Interests

Cancer; Cardiovascular Disease; Nutrition

Research Organizations

Internal Medicine: Digestive Diseases

Vascular Biology and Therapeutics Program

Research Summary

  1. Portal hypertension in liver diseases
  2. Liver fibrosis, regeneration, alcoholic and non-alcoholic fatty liver diseases
  3. Endothelial cell biology and nitric oxide signaling

Extensive Research Description

    1. Arterial remodeling in chronic liver diseases.
    2. Role of S-nitrosylation of the Golgi proteins in the function of endothelial cells.
    3. The mechanisms of the development of the hyperdynamic circulatory syndrome in patients with liver diseases.
    4. Role of Nogo-B in liver fibrosis and regeneration.
    5. Role of EMMPRIN (extracellular matrix metalloprotease inducer) in the pathogenesis of liver diseases.

    Selected Publications

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    Contact Info

    Yasuko Iwakiri, PhD
    Office Location
    The Anlyan Center
    300 Cedar Street, Ste S223B

    New Haven, CT 06519
    Mailing Address
    PO Box 208056
    333 Cedar Street

    New Haven, CT 06520-8056