Vincent James Quagliarello, MD

Professor of Medicine (Infectious Diseases); Clinical Chief, Infectious Diseases; Vice Chair for Education and Academic Affairs, Department of Internal Medicine

Research Interests

Endocarditis; Meningitis; Nursing Homes; Pneumonia; Infectious Disease Medicine

Research Organizations

Internal Medicine: Infectious Diseases

Faculty Research

Office of Cooperative Research

Research Summary

Dr. Quagliarello is a nationally recognized investigator in the pathophysiology and management of meningitis, and the prognostic classification and management of endocarditis. For the past several years, his scholarship has focused on infections among older adults as an NIH R01 funded principal investigator and a recipient of an NIH K07 Academic Leadership Award to mentor trainees at the postdoctoral and junior faculty level to develop interdisciplinary research at the interface of Infectious Diseases and Geriatrics.

Specialized Terms: Observational research methods for understanding infectious disease

Selected Publications

  • Dissemination of Neisseria meningitis Quagliarello V. Dissemination of Neisseria meningitis. N Engl J Med 2011;364:1573-5.
  • VanNess P, Peduzzi P, Quagliarello VJ. Efficacy and effectiveness as aspects of cluster randomized trials of nursing home residents: methodological insights from a pneumonia prevention trial. Cont Clin Trials 2012; 33:1124-31.
  • Ledizet M, Murray TS, Puttagunta S, Slade MD, Quagliarello VJ, Kazmierczak BI. The ability of virulence factor expression by Pseudomonas aeruginosa to predict clinical disease in hospitalized patients. PLoS ONE 2012; 7(11):e49578. doi: 10.1371/journal.pone.0049578. Epub 2012 Nov 12.
  • Juthani-Mehta M, De Rekeneire N, Allore H, Chen S, O’Leary J, Bauer DC,. Harris TB Newman AB, Yende S, Weyant RJ, Kritchevsky S, and Quagliarello VJ. Modifiable risk factors for pneumonia requiring hospitalization among community-dwelling older adults: The Health, aging, and body composition study. J Amer Geriatr Soc 2013; 61:1111-8.
  • Bikdeli B, Wang Y, Kim N, Desai MM, Quagliarello V, Krumholz HM. Trends in hospitalization rates and outcomes of endocarditis among Medicare beneficiaries J Amer Coll Card 2013, doi:10.1016/j.jacc.2013.07.071.
  • Malinas MF, Chen S, Allore HG, Quagliarello VJ. Outcomes among older adult liver transplantation recipients in the Model End-stage Liver Disease (MELD) era. Ann Transplant 2014; 19:478-87.
  • Juthani-Mehta M, Van Ness PH, McGloin J, Argraves S, Chen S, Charpentier P, Miller L, Williams K, Wall D, Baker D, Tinetti M, Peduzzi P, Quagliarello VJ. A cluster randomized controlled trial of a multicomponent intervention protocol for pneumonia prevention among nursing home elders. Clin Infect Dis 2015; 60:849-57.
  • Zapata H, Quagliarello VJ. The microbiota and microbiome in aging: potential implications in health and age-related diseases. J Amer Geriatr Soc 2015; 63:776-81
  • Barakat LA, Juthani-Mehta M, Allore H, Trentalange M, Tate J, Rimland D, Pisani M, Akgun KM, Goetz MB, Butt AA, Rodriguez-Barradas M, Duggal M, Crothers K, Justice AC, Quagliarello VJ. Comparing clinical outcomes in HIV-infected and uninfected older men hospitalized with community-acquired pneumonia. HIV Medicine 2015; 16:421-30.
  • Juthani-Mehta M, Van Ness PH, Bianco L, Rink A, Rubeck S, Ginter S, Argraves S, Charpentier P, Acampora D, Trentalange M, Quagliarello V, Peduzzi P. Effect of cranberry capsules on bacteriuria plus pyuria among older women in nursing homes: a randomized clinical trial. JAMA 2016; 316:1879-87.

Full List of PubMed Publications

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Contact Info

Vincent James Quagliarello, MD
Patient Care Location
Yale Infectious DiseasesYale New Haven Hospital
20 York Street

New Haven, CT 06510
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Mailing Address
PO Box 208022
300 Cedar Street

New Haven, CT 06520-8022