Varman T. Samuel MD

Associate Professor of Medicine (Endocrinology)

Research Interests

Fat Induced Hepatic Insulin Resistance; In vivo metabolism core of the mouse metabolic phenotyping center at YSM

Research Summary

Investigation of the mechanism by which hepatic fat accumulation alters the insulin signaling cascade and leads to hepatic insulin resistance

Selected Publications

  • Targeting sterol receptor coactivator-1 with antisense oligonucleotides increases insulin stimulated skeletal muscle glucose uptake in male rats. Cantley JL, Vatner DF, Galbo T, Madiraju A, Petersen M, Perry RJ, Kumashiro N, Guebr Egziabher F, Gattu AK, Stacy MR, Dione DP, Sinusas AJ, Ragolia L, Hall CE, Manchem VP, Bhanot S, Bogan JS, Samuel VT. Am J Physiol Endocrinol Metab. 2014 Aug 26:ajpendo.00148.2014. doi: 10.1152/ajpendo.00148.2014.
  • The emerging role of oestrogen-related receptor ? as a regulator of energy metabolism. Samuel VT. Diabetologia. 2014 Sep 26.

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