Mario Strazzabosco MD, PhD

Professor (Adjunct) of Medicine (Digestive Diseases); Director, Transplant Hepatology

Departments & Organizations

Yale Medical GroupStem Cell Center, Yale: Stem Cells and Tissue Repair; Tissue Specific Stem CellsCancer Center, Yale: Gastrointestinal Cancer ProgramTransplantation Center, Yale-New HavenInternal Medicine: Digestive Diseases: Hepatology: Viral Hepatitis Program

Research Interests

Epithelial Cell Biology, Pathophysiology of Diseases of the Biliary Tree, Liver Cell Therapy, Treatment of Liver Cancer more...


  • M.D., University of Padova, 1982
  • Ph.D., University of Milan, Italy, 1993

Selected Publications

  • Spirlì C., Fiorotto R., Song L., Santos-Sacchi J., Okolicsanyi L., Masier S., Rocchi L., Vairetti MP., De Bernard M., Melero S., Pozzan T., Strazzabosco M. 2005. Glibenclamide stimulates fluid secretion in rodent cholangiocytes through a CFTR-independent mechanism. Gastroenterology 129:220-233.
  • Lazaridis KN, Strazzabosco M, Larusso NF . 2004. The cholangiopathies: disorders of biliary epithelia. Gastroenterology 127(5):1565-77.
  • C. Spirlì, L. Fabris, E. Duner, R. Fiorotto, N.F. La Russo, A. Sonzogni, L. Okolicsanyi, Strazzabosco M. 2003. Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes. Gastroenterology 124:737-753.



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