Daniel C. Biemesderfer PhD

Research Scientist in Medicine (Nephrology)

Departments & Organizations

Internal Medicine

Research Interests

Proximal tubule; regulated intramembrane proteolysis; megalin; amyloid precursor protein more...


  • B.S., Millersville University, 1971
  • Ph.D., Yale University, 1991

Selected Publications

  • Li, Y., R. Cong, S. Mentone and D. Biemesderfer. “The COOH terminus of megalin regulates gene expression in opossum kidney proximal tubule cells.” Am J Physiol- Cell Physiology 295:C529-37, 2008.
  • Biemesderfer, D. Regulated intramembrane proteolysis of megalin: Linking urinary protein and gene regulation in proximal tubule. Kidney International 69:1717-1721, 2006.
  • Zou, Z., B. Chung, T. Nguyen, S. Mentone, B. Thompson and D. Biemesderfer. Linking receptor-mediated endocytosis and cell signaling: Evidence for regulated intramembrane proteolysis (RIP) of megalin in proximal tubule. J Biol Chem 279:34302-34310, 2004.



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