Ali Khaled Abu-Alfa, MD, FASN

Assistant Professor (Adjunct) of Medicine (Nephrology)

Research Organizations

Internal Medicine

Research Summary

My primary research interests are:

  1. The delivery and methods of peritoneal dialysis as well as patient choice in renal replacement therapy.
  2. Nephrogenic Systemic Fibrosis and Gadolinium Containing Contrast Agents. focusing on epidemiology, mechanism of disease, policy and risk reduction.
  3. Optimizing the care of patients with chronic kidney disease with particular focus on anemia management and treatment of CKD-Mineral Bone Disorders.

Extensive Research Description

I am primarily interested in improving the delivery and methods of peritoneal dialysis, especially Automated Peritoneal Dialysis and new dialysate solutions. I am also interested in optimizing the care of patients with chronic kidney disease (CKD) with particular focus on anemia management and CKD-MBD, and on the transition to the renal replacement therapy phase.
A recent and active interest has been Nephrogenic Systemic Fibrosis and its association with Gadolinium-based Contrast Agents, focusing on risk reduction and policy. An annual mutli-disciplinary international conference has been held at Yale for the past 3 years, devoted to the issue with the fourth meeting being held in May 2010 in collaboration with the New York Academy of Sciences.
Cancer-related kidney diseases and complications are also within my areas of interest.

  • Nephrogenic Systemic Fibrosis: Epidemiology, risk factors and risk estimation
  • Nephrogenic Systemic Fibrosis: Therapy
  • Nephrogenic Systemic Fibrosis and Imaging: Risk reduction and management
  • Nephrogenic Systemic Fibrosis and Imaging: Screening for at-risk patients in MRI
  • Anemia management in CKD and hospitalized patients
  • Peritoenal Dialysis Physiologic studies

Selected Publications

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Contact Info

Ali Khaled Abu-Alfa, MD, FASN
Mailing Address
Section of NephrologyPO Box 208029
330 Cedar Street

New Haven, CT 06520-8029