Pilot Feasibility Grants

The NIH P30 Liver Center grant provides for the annual submission of pilot projects (up to $25,000 direct costs each) from both Yale and non-Yale Liver Center investigators as approved by the Executive Committee.

The purposes of the pilots are to fund new initiatives, not ongoing research, and to support new investigators to pursue liver related research that should lead to a R01-type funding or other support at a later date. Projects utilizing Core Facilities and supporting young investigators are given priority if the science is equally meritorious. Investigators should meet one of the following criteria:

  1. Senior fellows or junior faculty at Yale, currently not funded by NIH grants and in need of funds to help prepare for R01-type applications.
  2. Established University investigators not currently funded for work related to the Center’s focus but who wish to apply their areas of expertise to subjects of Center interest.
  3. Funded Center investigators who wish to pursue a project that is different from their current focus of interest, and who need to develop preliminary data to apply for new R01-type funding.

An internal review by the Center’s Executive Committee must precede submission of pilot project requests to our External Advisory Board. This Board will convene at Yale in May to determine a priority score for each request and can approve or disapprove the project or modify the budget. According to our guidelines, no pilot projects can be submitted for more than two consecutive years. All current pilot project recipients must follow the same guidelines to request a second year of funding.

Important Dates

Please note the following dates on your calendar:

Friday, January 31, 2014. Deadline for submission of Letter of Intent (one electronic copy) emailed to Kathy Weisgable at kathleen.weisgable@yale.edu by 5:00pm.

The letter of intent must include the following:

  1. academic position, VISA status and future scientific plans regarding Digestive Diseases’ research;
  2. title of pilot project; and
  3. a sentence as to the applicability of the pilot project to the Liver Center.

Friday, February 28, 2014. Deadline for submission of full applications (one electronic copy) emailed to Kathy Weisgable at kathleen.weisgable@yale.edu by 5:00pm. This should include all documents listed below. Due to pilot projects being internally funded, a proposal summary (prosum) and Grants & Contracts approval/signature is not required.

Friday, April 11, 2014. Internal reviews of all applications are returned to investigators for revisions.

Wednesday, April 30, 2014. Receipt of revised application deadline (one electronic copy) emailed to Kathy Weisgable at kathleen.weisgable@yale.edu by 5:00 pm.

Thursday, May 15, 2014. External Advisory Board meets at Yale to make final decisions on awards. Applicants will be expected to present their pilot project to the Board on this date (approximately 15 minutes).

September 1, 2014. Approved projects will begin funding period.

Format of applications

The general format of the NIH research project applications on fillable individual PHS 398 forms (rev. 6/09) must be used to request pilot funding. Please only use forms listed below and submit in the order listed. To download forms, go to http://grants.nih.gov/grants/funding/phs398/phs398.html. If using the PDF forms, Adobe Acrobat 9 Professional software is necessary in order to save/edit your application on the required forms when submitting your application. Pilot project applications should not exceed the page limits and format below.

A. Form Page 1: Face Page
Q2. NumberNot Applicable
Q2. TitleYale Liver Center Pilot Project Program
Q6. Date of proposed period of supportsfrom 09/01/14 through 08/31/15
Q9. Applicant OrganizationName: Yale University
Address: 47 College St, Suite 203
PO Box 208047
New Haven CT -6520-8047
Q11., Q12. and Q13.Does not need to be completed
B. Form Pages and 3 (This is 2 pages)
Project Summary, Relevance, Project/Performance Sites, Additional Project/Performance Sites, Senior/Key Personnel, Other Significant Contributors, and Human Embryonic Stem Cells
C. Form Page 4Detailed Budget for Initial Budget Period – no PI salary allowed; salary may only be requested for project support personnel (for example; research/technical assistant). Cannot submit request for funding for travel or publications.
D. Resources Format Page
1 page limit
E. Specific Aims
½ page limit on continuation page
F. Background and Significance1 page limit on continuation page
G. Preliminary Results2 page limit on continuation page
H. Research Design and Methods2 page limit on continuation page
I. Biographical Sketch Format Pageone each for all key personnel  - 4 page limit
J. Other support for all key personnelon continuation page and follow format used in “Other Support Format Page”. Example at http://grants.nih.gov/grants/funding/phs398/othersupport.pdf.


If you have any questions, please contact me at 203-785-7352, email: michael.nathanson@yale.edu; Mario Strazzabosco at 203-785-7281, email: mario.strazzabosco@yale.edu; or Kathy Weisgable at 203-785-6140, or email: kathleen.weisgable@yale.edu.

The Liver Center website is: http://medicine.yale.edu/intmed/livercenter/index.aspx