Pilot Feasibility Grants

The NIH P30 Liver Center grant provides for the annual submission of pilot projects (up to $25,000 direct costs each) from both Yale and non-Yale Liver Center investigators as approved by the Executive Committee.

The purposes of the pilots are to fund new initiatives, not ongoing research, and to support new investigators to pursue liver related research that should lead to a R01-type funding or other support at a later date. Projects utilizing Core Facilities and supporting young investigators are given priority if the science is equally meritorious. Investigators should meet one of the following criteria, in order of priority:

  1. Senior fellows or junior faculty at Yale, currently not funded by NIH grants and in need of funds to help prepare for R01-type applications.
  2. Established University investigators not currently funded for work related to the Center’s focus but who wish to apply their areas of expertise to subjects of Center interest.
  3. Funded Center investigators who wish to pursue a project that is different from their current focus of interest, and who need to develop preliminary data to apply for new R01-type funding.

**We are also accepting submissions for special pilots specifically associated with some aspect related to the biology, pathogenesis, and/or therapy of primary sclerosing cholangititis including basic studies related to cholestasis**


An internal review by the Center’s Executive Committee must precede submission of pilot project requests to our External Advisory Board. This Board will convene at Yale in May to determine a priority score for each request and can approve or disapprove the project or modify the budget. According to our guidelines, no pilot projects can be submitted for more than two consecutive years. All current pilot project recipients must follow the same guidelines to request a second year of funding.

Important Dates

Please note the following dates on your calendar: 


Friday, January 22, 2016: Deadline for submission of Letter of Intent (one electronic copy) emailed to Christine Abu-Hanna at Christine.abu-hanna@yale.edu by 5:00pm.

The letter of intent must include the following: 

  1. **please specify if you are applying for the special pilot listed above**;
  2. Title of pilot project and
  3. A sentence as to the applicability of the pilot project to the Liver Center. 

Upon Letter of Intent review by the Executive Committee, applicants will be notified whether or not they can submit a full grant application; 

Friday, February 26, 2016: Deadline for submission of full applications (one electronic copy) emailed to Christine Abu-Hanna at Christine.abu-hanna@yale.edu by 5:00pm. This should include all documents listed below.
Due to pilot projects being internally funded, a TranSum and Office of Sponsored Projects approval/signature is not required. 

Friday, April 8, 2016: Internal reviews of all applications are returned to investigators for revisions. 


Friday, April 29, 2016: Receipt of revised application deadline (one electronic copy) emailed to Christine Abu-Hanna at Christine.abu-hanna@yale.edu by 5:00pm. 


Friday, June 2, 2016: External Advisory Board meets at Yale to make final decisions on awards. Applicants will be expected to present their pilot project to the Board on this date (approximately 15 minutes). 


September 1, 2016: Approved projects will begin funding period.

Format of applications

The general format of the NIH research project applications on fillable individual PHS 398 forms Rev. 8/12 approved through 8/31/2015 must be used to request pilot funding. Please only use forms listed below and submit in the order listed. To download forms, go to: http://grants.nih.gov/grants/funding/phs398/phs398.html. If using the PDF forms, Adobe Acrobat 9 Professional software is required in order to save/edit your application on the forms required when submitting your application. Only the pages listed below are required for this application.  Pilot project applications should not exceed the page limits and format below:
A. Form Page 1: Face Page
Q2. NumberNot Applicable
Q2. TitleYale Liver Center Pilot Project Program
Q6. Date of proposed period of supportsfrom 09/01/16 through 08/31/17
Q9. Applicant OrganizationName: Yale University
Address: 150 Munson Street, 3rd Floor
PO Box 208327
New Haven CT 06520-8327
Q11., Q12. and Q13.Does not need to be completed
B. Form Pages and 3 (This is 2 pages)Project Summary, Relevance, Project/Performance Sites, Additional Project/Performance Sites, Senior/Key Personnel, Other Significant Contributors, and Human Embryonic Stem Cells
C. Form Page 4PLEASE NOTE: no PI's salary allowed, a salary may only be requested for project support personnel (for example; research/technical assistant). Cannot submit request for funding for travel or publications.
D. Resources Format Page
1 page limit
E. Specific Aims
½ page limit on continuation page
F. Background and Significance1 page limit on continuation page
G. Preliminary Results2 page limit on continuation page
H. Research Design and Methods2 page limit on continuation page
I. Biographical Sketch Format Page

one each for all key personnel - 5 page limit
a.The following biosketch formats must be used. See http://grants.nih.gov/grants/funding/424/index.htm#biosketch

 
J. Other support for all key personnelon continuation page and follow format used in “Other Support Format Page”. Example at http://grants.nih.gov/grants/funding/phs398/othersupport.pdf.

Questions?

If you have any questions, please contact me at 203-785-7352, email: michael.nathanson@yale.edu; Mario Strazzabosco at 203-785-7281, email: mario.strazzabosco@yale.edu; or Christine Abu-Hanna at 203-785-5610, or email: christine.abu-hanna@yale.edu.

The Liver Center website is: http://medicine.yale.edu/intmed/livercenter/index.aspx