Jonathan S Bogan MD

Associate Professor of Medicine (Endocrinology) and of Cell Biology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development

Cell Biology: Membrane Traffic | Cytoskeletal Dynamics

Internal Medicine: Endocrinology: Diabetes Center | Diabetes Research Center

Research Interests

Protein trafficking; Ubiquitin-like modification; Cell structure; Insulin signaling; Type 2 diabetes; Metabolic diseases   more...


  • B.S., Yale University, 1986
  • M.D., Harvard Medical School, 1992

Selected Publications

  • Löffler MG, Birkenfeld AL, Philbrick KM, Belman JP, Habtemichael EN, Booth CJ, Castorena CM, Choi CS, Jornayvaz FR, Lee H-Y, Cartee GD, Booth CJ, Philbrick WP, Shulman GI, Samuel VT, and Bogan JS. Enhanced fasting glucose turnover in mice with disrupted TUG action in skeletal muscle. Journal of Biological Chemistry 2013; 288:20135-20150.
  • Bogan JS, Rubin BR, Yu C, Löffler MG, Orme CM, Belman JP, McNally LJ, Hao M, and Cresswell JC. Endoproteolytic Cleavage of TUG Protein Regulates GLUT4 Glucose Transporter Translocation. Journal of Biological Chemistry 2012; 287:23932-23947.
  • Bogan JS. Regulation of Glucose Transporter Translocation in Health and Diabetes. Annual Review of Biochemistry 2012; 81:507–32.



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