Research


Research is one of the cornerstones of our Section. Our Section currently has over $8 million per year in research funding from NIDDK, more than any other Digestive Diseases Section in the country. Our faculty are engaged in a wide range of both basic laboratory research activities and patient-oriented clinical research. Details of an investigators work can be found through links on our faculty menu.

Major areas of laboratory research include:

Major areas of clinical research include:

  • complications and treatment of cirrhosis (Drs. Roberto Groszmann, Guadalupe Garcia-Tsao), viral hepatitis (Dr. Joe Lim), liver cancer (Dr. Mario Strazzabosco), and IBD (Drs. Judy Cho and Deborah Proctor),
  • motility disorders of the esophagus, optimal application of advanced endoscopic techniques to clinical problems including gastrointestinal bleeding, graft-versus-host disease and pancreatic biliary disorders (Dr. Harry Aslanian),
  • advanced endoscopic techniques; pancreatitis; sphincter of oddi dysfunction as well as other clinical aspects of biliary and pancreatic disease (Dr. Priya Jamidar),
  • endoscopic outcomes research (Dr. Anil Nagar),
  • diverticulitis (Dr. Martin Floch), and
  • newer endoscopic modalities (Dr. Caroline Loeser).

Related programs include: 

Bio Profile

Clara Abraham, MD

Associate Professor of Medicine (Digestive Diseases)

Research Interests

Colitis, Ulcerative; Crohn Disease; Digestive System Diseases; Immune System; Intestines; T-Lymphocytes; Inflammatory Bowel Diseases

Bio Profile

Harry Aslanian, MD, FASGE, AGAF

Associate Professor of Medicine (Digestive Diseases)

Associate Director, Endoscopy

Director, Yale Advanced Endoscopy Fellowship

Research Interests

Biliary Tract Diseases; Colonic Polyps; Digestive System Diseases; Endoscopy; Gastrointestinal Hemorrhage; Pancreatic Cyst; Pancreatic Diseases; Pancreatic Neoplasms; Endoscopic Ultrasound-Guided Fine Needle Aspiration

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Henry Binder, MD

Professor Emeritus of and Senior Research Scientist in Medicine (Digestive Diseases)

Research Interests

Adenosine Triphosphatases; Digestive System Diseases; Epithelial Cells; Fatty Acids, Volatile; Ion Transport

Bio Profile

James Boyer, MD

Ensign Professor of Medicine (Digestive Diseases)

Emeritus Director, Yale Liver Center

Research Interests

Bile; Cholestasis; Digestive System Diseases; Hepatitis; Jaundice; Liver; Cholangitis, Sclerosing

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Judy Cho, MD

Director, Inflammatory Bowel Disease Center

Research Interests

Digestive System Diseases; Inflammatory Bowel Diseases

Bio Profile

Chuhan Chung, MD

Associate Professor of Medicine (Digestive Diseases)

Research Interests

Digestive System Diseases; Metabolic Diseases; Obesity; Angiogenesis Inhibitors

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Bio Profile

Guadalupe Garcia-Tsao, MD

Professor of Medicine (Digestive Diseases)

Chief, Digestive Diseases, VA-CT Healthcare System

Director, Clinical and Translational Core, Yale Liver Center

Program Director, VA-CT Hepatitis C Resource Center

Research Interests

Ascites; Digestive System Diseases; Gastroesophageal Reflux; Hepatitis C; Hepatorenal Syndrome; Liver Cirrhosis; Peritonitis; Veterans

Bio Profile

Fred Gorelick, MD

Professor of Medicine (Digestive Diseases) and of Cell Biology

Deputy Director, Yale M.D., Ph.D. Program

Research Interests

Cell Biology; Digestive System Diseases; Gastrointestinal Diseases; Pancreatic Diseases; Pancreatitis; Protein Kinase C; Pancreas, Exocrine; AMP-Activated Protein Kinases; Proteolysis

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Roberto Groszmann, MD

Professor Emeritus of Medicine (Digestive Diseases)

Research Interests

Ascites; Digestive System Diseases; Hypertension; Liver Cirrhosis