John Kiene Forrest MD

Assistant Professor of Medicine (Cardiology); Director, Structural Heart Disease Program

Research Interests

Transcather Aortic Valve Replacement (TAVR)

Research Summary


Co-investigator Medtronic CoreValve US Pivotal Trial (TAVR trial)

Co-investigator Levant II (Drug-eluting balloon)

Co-investigator Biotronic Biofex I (Peripheral stent)

Co-investigator Patient-Centered Outcomes Recovery from Treating PAD: Investigating Trajectories (PORTRAIT).

Co-investigator Carotid Stenting for High Surgical Risk Patients; Evaluating Outcomes Through the Collection of Clinical Evidence (CHOICE).

Co-investigator Angion BB3

Co-investigator Gilead RIVER-PCI

Co-investigator Tryton (side-branch stent) Trial

Selected Publications

  • Forrest JK. Transcatheter Aortic Valve Replacement: Design, Clinical Applications, and Future Challenges. Yale J Biol Med. 2012 Jun;85(2):239-47.
  • Milewski MI, Mickle JR, Forrest JK, Stafford DM, Moyer BD, Cheng J, Guggino WB, Stanton BA, Cutting GR. A PDZ-binding motif is essential but not sufficient to localize the C terminus of CFTR to the apical membrane. J Cell Sci. 2001 Feb;114(Pt 4):719-26.
  • Milewski MI, Mickle JR, Forrest JK, Stanton BA, Cutting GR. Aggregation of misfolded proteins can be a selective process dependent upon peptide composition. J Biol Chem. 2002 Sep 13;277(37):34462-70.

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