Arya Mani, MD, FACC, FAHA

Associate Professor of Medicine (Cardiology) and of Genetics; Director, Cardiovascular Genetics Program; Director, Cardiovascular Module

Physician Biography

As the Director of the Cardiovascular Genetics Program at Yale, I run a weekly outpatient clinic where I am involved in evaluation and management of patient with inherited cardiovascular diseases, supervision of the cardiovascular genetic counselor in providing consult to patients with inherited cardiovascular disease and in genetic testing, data analysis and diagnosis of the genetic disorder in these patients. I have established the first center for center for comprehensive testing of disease genes using the state of the art technology known as whole exome sequencing. We evaluate patients wih inherited arrhythmias, sudden cardiac death, Long QT syndrome, Brugada, Cardiomyopathy, inerited aortic diseases, coronary artery disease and lipid abnormalities and many othe inherited heart disease. We also manage the therapy of patients with lipid disorder, metabolic syndrome and coronary artery disease. We are the only center that has identified the cause of hereditary metabolic syndrome.

Clinical Interests

  • Adult
  • Cardiology
  • Cardiovascular Diseases
  • Cholesterol
  • Diabetes Mellitus
  • Diabetes Mellitus, Type 1
  • Diabetes Mellitus, Type 2
  • Echocardiography
  • Electrocardiography
  • Genetic Counseling
  • Genetics
  • Heart Defects, Congenital
  • Heart Diseases
  • Heart Failure
  • Heart Valve Diseases
  • Hypertension
  • Mitral Valve Prolapse
  • Syncope
  • Electrocardiography, Ambulatory
  • Inheritance Patterns
  • Atherosclerosis

Patient Care

Accepts new patients? Yes
Patient Type: Adult
Referrals: From patients or physicians

Patient Care Organizations


Heart & Vascular Center, Yale-New Haven Hospital

Internal Medicine: Cardiovascular Medicine: Cardiomyopathy Inherited Cardiovascular Disease Program; Cardiovascular Genetics Program; Echocardiography (Cardiac Imaging)

Yale Medical Group

Board Certifications

  • Cardiovascular Disease AB of Internal Medicine (2001)

  • Internal Medicine AB of Internal Medicine (1996)

  • Adult Transthoracic Plus Stress Echocardiography National Board of Echocardiography (2008)

Clinical Trials

Conditions Study Title
The Pathophysiology of the Inherited Metabolic Syndrome

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Contact Info

Arya Mani, MD, FACC, FAHA
Patient Care Locations
Yale-New Haven Hospital
20 York Street

New Haven, CT 06510
Yale CardiologyYale Physicians Building
800 Howard Avenue, Ste 2nd floor

New Haven, CT 06519
Lab Location
Mani's Lab300 George Street, Ste 759
New Haven, CT 06511
Mailing Address
PO Box 208056
333 Cedar Street

New Haven, CT 06520-8056