Yale New-Haven Hospital provides a full range of inpatient and outpatient arrhythmia management services. Facilities include two electrophysiology laboratories for device-based and interventional electrophysiology management, operating rooms for pacemaker and ICD implantation, and numerous clinics for outpatient evaluation.

Current Research

Current electrophysiology research at Yale includes studies investigating:

Prevention of embolization from the left atrial appendage (LAA) in patients with atrial fibrillation

  • Amplatzer Cardiac Plug Trial – An evaluation of a percutaneously-delivered cardiac plug compared with medical therapy in patients with nonvalvular atrial fibrillation

Atrial fibrillation

  • Cardiothoracic Surgical Trials Network Atrial Fibrillation Trial – A trial of surgical ablation versus no ablation for patients with persistent atrial fibrillation undergoing mitral valve surgery
  • ZERO AF - Clinical Evaluation of the Blazer Open-irrigated Ablation Catheter for the Treatment of Paroxysmal Atrial Fibrillation
  • ORBIT AF - Orbit AF - Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II


  • Medtronic Sure Scan Registry – A registry of patients implanted with the MRI-safe EnRhythm MRI and Advisa MRI Sure Scan pacing systems
  • PROMRI - ProMRI Study
  • SIELLO- SIELLO Clinical Study
  • MICRA - Medtronic Micra Transcatheter Pacing Study
  • WRAP IT - Cardiovascular Implantable Electronic Device (CIED) Antibiotic Envelope Infection Prevention Trial
  • MagnaSafe Registry- MagnaSafe Registry:  Determining the Risks of MRI in the Presence of Pacemakers and Implantable Cardioverter Defibrillators

ICD remote monitoring determinants and outcomes

  • An investigation of the determinants and impact of the use of remote monitoring technology in patients with implantable cardioverter-defibrillators (ICDs) using the American College of Cardiology National Cardiovascular Data Registry and Medicare claims databases.
  • REFINE ICD - Risk Estimation Following Infarction Noninvasive Evaluation - ICD efficacy
  • WISDOM - An Intervention to Improve Implantable Cardioverter-Defibrillator Deactivation Conversations
  • ICD Sports Registry- Safety of Sports for Patients with Implantable Cardioverter  Defibrillators:  A Multicenter Registry
  • 4 Site - The Longitudinal Surveillance Study of 4-SITE Lead/Header System

Cardiac resynchronization therapy (CRT)

  • An investigation of the clinical outcomes of patients undergoing CRT
  • NAVIGATE - Evaluation of ACUITY X4 Quadripolar Coronary Venous Leads and RELIANCE 4-FRONT Defibrillation Leads NAVIGATE X4 Clinical Study

Congestive Heart Failure

  • FIX HF - Evaluate Safety and Efficacy of the OPTIMIZER® System in Subjects With Moderate-to-Severe Heart Failure: FIX-HF-5C


  • Sarcoid Registry - Development of a Prospective Cardiac Sarcoidosis Registry

Device Registry

  • PSR - Medtronic Product Surveillance Registry


Bio Profile

Joseph Akar, MD, PhD

Associate Professor of Medicine (Cardiology)

Academic Director of Electrophysiology

Director, Cardiac Electrophysiology Laboratory

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Bio Profile

William Batsford, MD

Professor Emeritus of Medicine (Cardiology)

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Jude Clancy, MD

Assistant Professor of Medicine (Cardiology)

Director, Lead Management Program

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Mark Marieb, MD

Associate Professor of Medicine (Cardiology) and Associate Clinical Professor of Nursing

Clinical Director of Electrophysiology

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