Coronary Intervention


The Yale-New Haven Hospital/Yale University interventional cardiology program is nationally and internationally recognized for its expertise in diagnostic cardiac catheterization and complex percutaneous coronary intervention. YNHH performs more than 3,000 diagnostic and more than 1,800 interventional procedures annually at five state of the art catheterization laboratories employing 13 interventional cardiologists.

Current Research

Eight studies of coronary interventional devices and adjunctive pharmacotherapy are currently being conducted at Yale. Topics of ongoing and recent studies include:

Drug-eluting stents

  • PROTECT Continued Access – A post market surveillance trial of patients treated with a zotarolimus-eluting coronary stent system
  • Tryton Side Branch Stent Study – A comparison of a dedicated side branch stent plus drug-eluting stent (DES) implantation with balloon angioplasty and DES to treat de novo bifurcation lesions

Chronic total occlusions

  • FAST-CTO – A multicenter study of a new facilitated anterograde steering technique to cross coronary artery chronic total occlusions
  • Expert CTO – A evaluation of the Xience everolimus-eluting coronary stent system in the treatment of chronic total occlusions

Adjunctive pharmacotherapy

  • NIH-Angion – A Phase II study of the use of a novel renoprotective drug as an adjunct to percutaneous coronary intervention for ST-segment elevation myocardial infarction

Appropriateness criteria

  • Predict Outcomes – A study to develop and evaluate the implementation of appropriateness criteria for percutaneous coronary intervention

Invasive imaging modalities

Investigations of:
  • Intravascular ultrasound (IVUS)
  • Optical coherence tomography (OCT)
  • Virtual Histology Imaging


Meier, Pascal
Interventional Cardiologist