Gerald S Shadel, PhD
Professor of Pathology and of Genetics; Director, Graduate Studies Experimental Pathology Graduate Program
Departments & Organizations
Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Molecular Medicine, Pharmacology, and Physiology
Pathology
Genetics
Research Interests
Mitochondrial Genetics and Biogenesis; Mitochondrial Dysfunction in Human Disease and Aging; Mechanisms of mtDNA Transcription and Mitochondrial Translation; Signaling Pathways that Sense and Control Mitochondrial Function more...
Education
- B.S., University of Nevada, Las Vegas, 1986
- Ph.D., Texas A & M University, 1991
Selected Publications
- Pan Y, Schroeder EA, Ocampo A, Barrientos A, Shadel GS. (2011) Regulation of Yeast Chronological Life Span by TORC1 via Adaptive Mitochondrial ROS Signaling. Cell Metabolism 13:668-78
- Woo DK, Shadel GS. (2011) Mitochondrial stress signals revise an old aging theory. Cell 144:11-2.
- West AP, Brodsky IE, Rahner C, Woo DK, Erdjument-Bromage H, Tempst P, Walsh MC, Choi Y, Shadel GS, Ghosh S. (2011) TLR signalling augments macrophage bactericidal activity through mitochondrial ROS. Nature. 472:476-80.
