Clinical Investigation

Clinical investigation at Yale bridges the gap between the basic and translational sciences and the practice of medicine. Research is focused on the factors that affect health and illness in populations, the evaluation of therapeutic interventions, and the assessment of health outcomes based on analysis of large data sets. The School of Medicine sponsors a wide range of clinical trials, with more than 500 open trials in 2014 with more than 3,800 volunteers enrolled (see the Clinical Research at Yale website). The school offers superb training for clinical investigators in a number of settings, including the Yale Center for Clinical Investigation, the Robert Wood Johnson Clinical Scholars Program at Yale, the Yale School of Public Health, and the Investigative Medicine Program, along with discipline-specific training initiatives in selected departments.

The Yale Center for Clinical Investigation facilitates the training of clinical and translational scientists and provides infrastructure for innovative and collaborative research directed at improving patient care. It funds up to 23 YCCI Scholars yearly and supports investigators in the areas of biostatistics, bioinformatics, study design, core technologies, regulatory review, patient recruitment, and community-based research. Yale was one of the first 12 institutions to launch the Clinical and Translational Science Awards program in 2006.

The Robert Wood Johnson Foundation Clinical Scholars Program at Yale was established in 1974 to prepare future physician leaders who will improve health and health care. Graduates of the two-year fellowship earn a master of health sciences research (MHS) degree.

The School of Public Health offers training and conducts research in biostatistics, chronic disease epidemiology, environmental health sciences, epidemiology of microbial diseases, and health policy and administration.

The Investigative Medicine Program awards a PhD degree to holders of MD degrees who pursue training in either laboratory-based or clinically based human investigation.

By the numbers

RWJ Scholars since 1974179
PhDs awarded by Investigative Medicine Program since 200330
YCCI Scholars trained since 2006100

All data in Facts & Figures as of 6/30/14, unless otherwise noted.

Community research

Researchers conducting clinical trials benefit from numerous central resources, including patient recruitment ads on Yale shuttles and Metro North trains.