Brian Richard Smith, MD

Professor of Laboratory Medicine, of Biomedical Engineering, of Medicine (Hematology) and of Pediatrics; Chair, Department of Laboratory Medicine

Departments & Organizations

Cancer Center, Yale: Cancer Immunology

Center for X-Linked Hypophosphatemia, Yale

Immunology and Immunotherapy

Internal Medicine

Laboratory Medicine: Clinical Hematology | Clinical Immunology | Hematology Laboratory | Immune Monitoring Core Facility

LCME Institutional Self-Study Task Force: LCME Education Subcommittee

Office of Student Research

Program for Biomedical Ethics

Yale Medical Group


Brian R. Smith MD is Chair of the Department of Laboratory Medicine at the Yale School of Medicine and Professor of Laboratory Medicine, Biomedical Engineering, Internal Medicine and Pediatrics at Yale University. He is also the Chief of Laboratory Medicine at Yale New Haven Hospital.

Dr. Smith received his undergraduate degree from Princeton University, his medical degree from the Harvard Medical School, and his residency/fellowship training at The Brigham & Women’s Hospital, Boston Children’s Hospital, and Dana Farber Cancer Center. He is board certified in Pathology / Hematopathology and in Internal Medicine / Hematology-Oncology. In addition to his clinical work, Dr. Smith has an investigative interest in the inflammation-coagulation interface, especially in relation to biomaterials, as well as in cellular immunotherapeutics, with over 175 publications. His educational activities include direction of an NIH-funded research training program in Immunohematology and Transfusion Medicine and he also occasionally lectures in the areas of biomedical ethics, “therapeutic pathology”, and in the education of the physician-scientist.

Education & Training

MD Harvard University (1976)
BA Princeton University, Chemistry (1972)
Fellow Brigham & Women's Hospital/Dana Farber Cancer Center/Children's Hospital,Boston
Resident Brigham & Women's Hospital/Harvard Medical School

Honors & Recognition

  • Evans Award for Outstanding Contributions to Laboratory Medicine Academy of Clinical Laboratory Physicians & Scientists (2010)

  • President, Academy of Clinical Laboratory Physicians & ScientistsAcademy of Clinical Laboratory Physicians & Scientists (2007), (2008)

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Contact Info

Brian Richard Smith, MD
Patient Care Location
Yale Laboratory Medicine55 Park Street, Ste Suite 218
New Haven, CT 06519
Office Locations
Main Office, Department of Laboratory MedicineClinic Building
789 Howard Avenue, Ste Rm 407

New Haven, CT 06519
Chair's Office, Department of Laboratory Medicine55 Park Street, Ste Rm 218
New Haven, CT 06519
Mailing Address
PO Box 208035
New Haven, CT 06520-8035

Curriculum Vitae