The driving force behind developmental biology is to understand how a single cell differentiates into a multicellular, regionalized yet integrated organism with many specialized parts. The development of a new life is a spectacular process that requires exquisite regulation of multiple cascades of temporal and spatial gene expression. Deciphering the cellular, genetic and molecular mechanisms underlying these processes is at the forefront of basic science research and is of direct and fundamental relevance to human development, disease, and stem cell therapy.
The findings of developmental biology have begun to help us understand the cellular and genetic mechanisms that underlie human syndromes and continue to inform us about human diseases. In addition, insights from cellular differentiation and stem cell maintenance during development hold the promise for regenerative medicine. The Interdepartmental Program in Developmental Biology encompasses both basic and translational science with the ultimate goal of understanding basic mechanisms of organ development and what goes awry during disease states.
Molecular Cell Biology, Genetics & Development: http://bbs.yale.edu/molecularcell/index.aspx.
BBS program: http://bbs.yale.edu/index.aspx.