Center for Outcomes Research & Evaluation (CORE)

We are a leading national outcomes research center working on select projects designed to assess healthcare quality and evaluate clinical decision making and comparative effectiveness of specific healthcare interventions. Our mission is to improve health and health care through targeted research and evaluation projects that combine scholarship and service to have a positive impact on policy and people’s lives.

A Sample of Current Projects at CORE:



Hospitalomics, funded by a 4-year Donaghue Foundation grant, is a multi-disciplinary data-driven approach that combines systems thinking, outcomes sciences, and information sciences to generate information on variation in hospital care and to identify those patterns of care that are strongly associated with the best performance as measured by clinical outcomes (mortality and...




In 2010, the National Heart, Lung, and Blood Institute of the National Institutes of Health established a Center for Cardiovascular Outcomes Research at Yale University, one of three identified after a national competition. CCOR’s 4-year grant will provide the research infrastructure to develop a national surveillance program for cardiovascular care and outcomes.


Quality Measurement


Our Quality Measurement Group's ongoing work with the Centers for Medicare & Medicaid Services (CMS) includes new measure development, research on hospital quality including evaluation of trends, disparities and geographic variation and communications with stakeholders about hospital quality, and potential expansion of outcomes measures to other health care settings.




Women 55 years and younger have about twice the risk of death from a heart attack than similarly aged men. Our VIRGO group has been funded by the National Institutes of Health to examine predictors of a broad range of early and 1-year outcomes for young women with heart attacks and to examine such questions as: Do women get the same quality of care as men?


(CORE) Readmission Risk Calculators iPhone App - It's Free!

The (CORE) Readmission Risk Calculators iPhone® App predicts a patient’s likelihood of hospital readmission within 30 days of discharge for heart attack, heart failure, or pneumonia. These calculators estimate risk of readmission based on a patient’s demographic and clinical characteristics and are based on medical record chart models developed for the Centers for Medicare and Medicaid Services to validate the publicly reported readmission measure for each condition. The app is in response to requests from users of our Online Readmission Risk Calculators. It also allows users to both save and email readmission risk data for later use. The app is available as a free download from the App StoreSM.