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Founded in 1995, CORE is one of the country’s original outcomes research centers. Led by Dr. Harlan M. Krumholz and Dr. Jennifer A. Mattera, CORE consists of talented clinical investigators, statisticians, analysts, computer scientists, economists, epidemiologists, management experts and administrative staff. We actively collaborate with national and international experts in outcomes research. CORE has recognized expertise in evaluating and improving quality of care, determining cost-effective strategies, tracking trends in patterns of care, developing and evaluating disease management and decision support tools, characterizing risk, profiling hospital performance, and evaluating the effectiveness of health care strategies. CORE’s projects have focused on the safety, effectiveness, efficiency, equity, timeliness, and patient-centeredness of health care delivery.