Caroline J. Zeiss, BVSc, PhD

Associate Professor Comparative Medicine, Ophthalmology
Director, Mouse Research Pathology Service

Yale University School of Medicine
PO Box 208016
New Haven, CT 06520-8016

Phone: (203) 737-4303
Fax: (203) 785-7499
Email: caroline.zeiss@yale.edu

Campus Location: LSOG 126

Education

• BVSc, University of Pretoria
• Intern, University of Pennsylvania
• Resident, Cornell University
• PhD, Cornell University

Research Interests

Molecular and cellular pathogenesis of retinal degeneration, neurobiology of movement disorders, phenotypes of genetically engineered mice, and evolutionary biology of the eye.

Clinical Specialties

• Veterinary Pathology
• Mouse Phenotyping
• Occular Pathology 

Publications of Note

Wang J, Farr GW, Zeiss CJ, Rodriguez-Gil DJ, Wilson JH, Furtak K, Rutkowski DT, Kaufman RJ, Ruse CI, Yates JR 3rd, Perrin S, Feany MB, Horwich AL (2009) Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS. Proc Natl Acad Sci U S A. 106(5):1392-7.

Bennicelli J, Wright JF, Komaromy A, Jacobs JB, Hauck B, Zelenaia O, Mingozzi F, Hui D, Chung D, Rex TS, Wei Z, Qu G, Zhou S, Zeiss C, Arruda VR, Acland GM, Dell'Osso LF, High KA, Maguire AM, Bennett J (2008) Reversal of blindness in animal models of leber congenital amaurosis using optimized AAV2-mediated gene transfer. Mol Ther. 16(3):458-65.

Singh B, Wilson JH, Vasavada HH, Guo Z, Allore HG, Zeiss CJ (2007) Motor deficits and altered striatal gene expression in aphakia (ak) mice. Brain Res. 1185:283-92.

Zeiss CJ, Allore HG, Towle V, Tao W (2006) CNTF induces dose-dependent alterations in retinal morphology in normal and rcd-1 canine retina. Exp Eye Res. 82(3):395-404.

Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, Henning AK, SanGiovanni JP, Mane SM, Mayne ST, Bracken MB, Ferris FL, Ott J, Barnstable C, Hoh J (2005) Complement factor H polymorphism in age-related macular degeneration. Science. 308(5720):385-9.