James McGrath, MD, PhD

McGrath, JamesMcGrath, James 

Research Scientist
Director, Animal Genomics Services
Director Medical Genetics Residency Program

Yale University School of Medicine
PO Box 208016
New Haven, CT 06520-8016

Phone: (203) 785-2686
Email: james.mcgrath@yale.edu

Campus Location: LSOG 120

Education

  • MD, Temple University
  • PhD, Temple University

Research Interests

Developmental Genetics

Clinical Specialty

Clinical Genomics

Publications of Note

Lin ZP, Zhu YL, Johnson DR, Rice KP, Nottoli T, Hains BC, McGrath J, Waxman SG, Sartorelli AC (2008) Disruption of cAMP and prostaglandin E2 transport by multidrug resistance protein 4 deficiency alters cAMP-mediated signaling and nociceptive response. Mol Pharmacol. 73(1):243-51.

Shaikh TH, O'Connor RJ, Pierpont ME, McGrath J, Hacker AM, Nimmakayalu M, Geiger E, Emanuel BS, Saitta SC (2007) Low copy repeats mediate distal chromosome 22q11.2 deletions: sequence analysis predicts breakpoint mechanisms. Genome Res. 17(4):482-91.

Hallaq H, Pinter E, Enciso J, McGrath J, Zeiss C, Brueckner M, Madri J, Jacobs HC, Wilson CM, Vasavada H, Jiang X, Bogue CW (2004) A null mutation of Hhex results in abnormal cardiac development, defective vasculogenesis and elevated Vegfa levels. Development. 131(20):5197-209.

McGrath J, Somlo S, Makova S, Tian X, Brueckner M (2003) Two populations of node monocilia initiate left-right asymmetry in the mouse. Cell. 114(1):61-73.

McGrath J, Solter D (1984) Completion of mouse embryogenesis requires both the maternal and paternal genomes. Cell. 37(1):179-83.

Links of Interests