Faculty

The Section of Comparative Medicine is a multidisciplinary faculty of veterinarians, physicians and scientists using cutting edge laboratory and clinical investigation to understand and treat disease.

Booth, Carmen Jane

Assistant Professor of Comparative Medicine
Co-director, Mouse Phenotyping Service

Research Interests:Pathology of genetically engineered mice; Pathology of inflammation; Pathology of aging; Veterinary Pathology; Mouse pathology; phenotyping; Hemophilia in rats

Brandsma, Janet L

Associate Professor (Adjunct) of Comparative Medicine and of Pathology

Research Interests:Molecular biology of papillomavirus pathogenesis; Development of protective and therapeutic vaccines for the treatment of human papillomavirus (HPV)-associated disease; Vaccines; Virology

Compton, Susan R

Research Scientist in Comparative Medicine
Director, Molecular, Serological and Virological Diagnostics

Research Interests:Pathogenesis of rodent viral infections; Diagnostic Virology; Bacterial Expression Systems; Communicable Diseases; Disease Control; Disease Model; Eukaryotic Expression Systems; Gastrointestinal Infection; Host Organism Interaction; Immunization; Immunoassay; Infectious Diseases/Agents; Intestinal Mucosa; Laboratory Mouse; Laboratory Rat; Molecular Probes; Murine Hepatitis Virus; Norovirus; Parvovirus; Pathogenesis; Polymerase Chain Reaction; Rat Coronavirus; Receptor Binding; Respiratory Diseases; RT-RCR; Serology; Sialodacryoadenitis Virus; Site Directed Mutagenesis; Vaccine; Viral Studies; Virion; Virology; Virulence; Virus Infection Mechanism; Virus Protein; Virus Receptor; Western Blotting

Dixit, Vishwa Deep

Professor of Comparative Medicine and of Immunobiology

Research Interests:Immune-Metabolic Interactions, Aging and age-related inflammation, Obesity-associated inflammation and metabolic syndrome, Adipose tissue leukocytosis, Inflammasomes, Thymic involution and approaches for thymic rejuvenation, Neuroendocrine control of immune system

Fernandez-Hernando, Carlos

Associate Professor of Comparative Medicine

Research Interests:Cholesterol homeostasis, Lipoprotein metabolism, Post-transcriptional regulation, microRNAs, Atherosclerosis, RNAi screening

Gao, Xiao-Bing

Associate Professor of Comparative Medicine and of Obstetrics, Gynecology, and Reproductive Sciences

Research Interests:Neurotransmission; Neurotransmitter response and synaptic plasticity; Cellular physiology of neuropeptides (hypocretin/orexin, melanin concentrating hormone, neuropeptide Y, ghrelin, leptin, and a-MSH); Ion channels (Na+, Ca2+, K+ channels); Electrophysiology/patch clamp recording; calcium imaging; Hypothalamus/lateral hypothalamic area; Energy homeostasis/feeding regulation; Sleep homeostasis and regulation; Drug addiction

Goodrich, James A

Assistant Professor of Comparative Medicine

Research Interests:Animal Models of Menopause; Cardiovascular Disease

Hajos, Mihaly

Professor (Adjunct) of Comparative Medicine

Research Interests:systems neurophysiology; biomarkers; schizophrenia; Alzheimer's disease, Huntington's disease, neuropharmacology

Horvath, Tamas L.

Jean and David W. Wallace Professor of Comparative Medicine and Professor of Neurobiology and of Obstetrics, Gynecology, and Reproductive Sciences
Chair, Section of Comparative Medicine
Director, Yale Program in Integrative Cell Signaling and Neurobiology of Metabolism

Research Interests:Neurobiology of obesity; Neuroendocrine physiology

Jacoby, Robert O

Professor Emeritus of Comparative Medicine
Chief, Clinical Services, Yale Animal Resources Center

Research Interests:Pathogenesis of rodent viral infections; Laboratory Animal Pathology; Vivarium Management; Laboratory Animal Medicine; Pathology

Lawrence, Matthew Swan

Assistant Professor (Adjunct) of Comparative Medicine

Research Interests:Pharmakokinetics; Emerging Therapeutics; Ophthalmology; Gene Therapy

Levy, Ifat

Assistant Professor of Comparative Medicine and of Neurobiology

Research Interests:Decision-making; Value; Reward; Risk; Ambiguity; Functional MRI

Macy, James D, Jr

Professor of Comparative Medicine
Vice Chairman for Clinical Affairs, Comparative Medicine
Attending Veterinarian
Director, Yale Animal Resources Center

Research Interests:Pathogenesis; Prevention of mouse parvovirus infection; Laboratory Animal Medicine

McGrath, James Michael

Research Scientist in Comparative Medicine, in Genetics and in Pediatrics

Research Interests:Developmental Genetics; Genetic Imprinting; Embryogenesis; Spermatogenesis

Nottoli, Timothy P

Research Scientist in Comparative Medicine
Co-director, Animal Genomics Services

Research Interests:Developmental Genetics; Animal Genomics; Gene Targeting and Transgenic Technology; Stem Cell Biology

Rodeheffer, Matthew S

Assistant Professor of Comparative Medicine and of Molecular, Cellular, and Developmental Biology

Research Interests:Genomics; Stem Cells

Scholz, Jodi Ann

Assistant Professor of Comparative Medicine

Research Interests:Environmental Enrichment; Laboratory Animal Medicine

Sleeman, Mark W

Professor (Adjunct) of Comparative Medicine

Research Interests:Physiology; Genomics

Smith, Peter C

Associate Professor of Comparative Medicine
Director, Residency Training Program

Research Interests:Epidemiology of rodent Infectious diseases; Laboratory Animal Medicine

Suarez, Yajaira

Assistant Professor of Comparative Medicine and of Pathology

Research Interests:Vascular Biology; Angiogenesis; Inflammation; Cholesterol homeostasis; Endothelial cells, Macrophages; Non-coding RNAs; Post-transcriptional regulation of Gene expression; MicroRNAs

Wilson, Steven R

Assistant Professor of Comparative Medicine

Research Interests:Virology and vaccine production; Laboratory Animal Medicine

Yang, Xiaoyong

Associate Professor of Comparative Medicine and of Cellular and Molecular Physiology

Research Interests:Nutrient Sensing; Cell Signaling; Circadian Rhythms; Post-translational Modifications; Metabolic Physiology; Diabetes; Cancer; Aging; Systems Biology

Yao, Gang-Qing

Research Scientist in Comparative Medicine
Director, Vector Design and Engineering Service

Research Interests:Molecular Biology of Bone Metabolism; Bone Metabolism; Endocrine effects on bone loss

Zeiss, Caroline J

Professor of Comparative Medicine and Associate Professor of Ophthalmology and Visual Science
Director, Mouse Research Pathology Service
Unit Chief, Pathology

Research Interests:Molecular and cellular pathogenesis of retinal degeneration; Neurobiology of movement disorders; Phenotypes of genetically engineered mice; Evolutionary biology of the eye; Veterinary Pathology; Mouse Phenotyping; Ocular pathology with emphasis on photoreceptor disorders; Neuroanatomy of age-related gait disorders; Signal transduction events during neuronal death; Comparative pathology with emphasis on murine neuroanatomy; Phenotying genetically altered rodents