Fees

Effective November 1, 2015


Yale Investigator


CRISPR/Cas Genome Editing
Option 1, guaranteed rate (contact Center for details)


CRISPR/Cas KO
$5900

CRISPR/Cas point mutation, knock-in
$7000

CRISPR/Cas conditional KO (flox)
$9000

Option 2, fixed rate (contact Center for details)


CRISPR/Cas KO
$5350

CRISPR/Cas point mutation, knock-in$5350

CRISPR/Cas conditional KO (flox)$5350

Transgenic Mouse Service$4300
Transgenic vector purification
$311

BAC, add:
$750

Alternate strain (e.g. C57BL/6), add:
$825

Transgenic, Gene Targeting Vector Construction$2500 - 8000

Gene Targeting Service
ES cell gene targeting (est; see below)
$15000

ESC chimera production from repository targeted clone 

(est; see below)

$5500

Electroporation, drug selection
$998

Electroporation, alternate ES Strain (e.g. C57BL/6)
$1103

Expansion of ES colonies, freezing (per clone) 
$15.50

Expansion of ES colonies, freezing (per clone), 

alternate ES strain (e.g. C57BL/6)

$16.28

Expansion of positive clones (per clone)
$305

de novo derivation of ES cells (per line)
$790

Freezing of additional vials (ES/MEF) (per vial)
$7.72

Consulting/Custom Services (Hourly)$98

Chimera Production
C57BL/6 donor (standard) (fee per embryo)
$29

Embryo transfer (per dam)
$131

Tail biopsy for genotyping
$8.14

Cryopreservation
Cryopreservation - Embryo (plus animal purchase cost)
$105/hr

Cryopreservation - Sperm (3 adult males)
$998

Embryo thaw/rederivation (plus animal purchase cost)
$499

Strain reanimation (IVF)
$735

Liquid nitrogen storage (charged per year, per investigator)
$150


Non-Yale Investigators: please contact us for prices and scheduling